Small doses of sevoflurane were administered for cardiac protection (De Hert et ah, 2002) despite the fact that it augmented neuromuscular block
in myasthenic patients (Baraka et ah, 2000; Itoh & Shibata, 2001).
Then, if neuromuscular block
is present, the 4th and 5th fingers will not move; on the other hand, if normal neuromuscular transmission is present, the typical picture of main-en-griffe will result.
Reversal of rocuronium-induced neuromuscular block
with sugammadex is faster than reversal of cisatracurium-induced block with neostigmine.
Duration of rocuronium-induced neuromuscular block
during liver transplantation: a predictor of primary allograft function.
Certain inhalation anesthetics, particularly enflurane and isoflurane, antibiotics, magnesium salts, lithium, local anesthetics, procainamide and quinidine, have been shown to increase the duration of neuromuscular block
and decrease infusion requirements of neuromuscular blocking agents.
Nevertheless, differentiating those selecting this reason for the use of monitoring could only reduce the numbers of practitioners objectively confirming full recovery from neuromuscular block
The second category is the use of rocuronium and the pre-planned reversal by sugammadex instead of neostigmine as a strategy to provide rapid and complete reversal of non-depolarising neuromuscular block
in situations where even subclinical residual neuromuscular block
may be harmful.
Table 1 Demographic data of patients undergoing an operation requiring intubation with neuromuscular block
for two six-week periods during restricted and unrestricted availability of sugammadex for neuromuscular block
reversal Variable Restricted, n (%) Age ** 141 <31 20 (14.
Sugammadex rapidly reverses moderate rocuronium- or vecuronium-induced neuromuscular block
during sevoflurane anaesthesia: a dose-response relationship.
ENLON(R) is also useful whenever a curare antagonist is needed to reverse the neuromuscular block
produced by curare, tubocurarine, gallamine triethiodide or dimethyl-tubocurarine.
Optimal dose of sufentanil in children for intubation after sevoflurane induction without neuromuscular block