neurolymphomatosis

neu·ro·lym·pho·ma·to·sis

(nū'rō-lim'fō-mă-tō'sis),
Lymphoblastic invasion of a nerve.
Farlex Partner Medical Dictionary © Farlex 2012

neurolymphomatosis

A rare lymphoma with a predilection for peripheral and cranial nerves, lumbar and brachial plexi and nerve roots, meninges, and vessels in the brain;12 of cases are accompanied by systemic lymphoma, which may be clinically silent; NLM may present as a painful chronic sensorimotor neuropathy with asymmetric distribution and prominent bulbar involvement; it is associated with HIV and HTLV-I infections
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.

neurolymphomatosis

(nū″rō-lĭm″fō-mă-tō′sĭs) [″ + L. lympha, lymph, + Gr. oma, tumor, + osis, condition]
Malignant lymphoma involving the nervous system.
Medical Dictionary, © 2009 Farlex and Partners
References in periodicals archive ?
Neurolymphomatosis (NL) is a rare condition of lymphomatous infiltration of peripheral nervous system, usually by B-cell non-Hodgkin lymphoma (NHL).
Negative sural nerve biopsy in neurolymphomatosis. J Neurol.
Neurolymphomatosis: diagnosis, management, and outcomes in patients treated with rituximab.
To the Editor: Neurolymphomatosis (NL) is a clinical disorder that presents with peripheral neuropathy due to lymphomatous infiltration of the nerves.
Neurolymphomatosis: An international primary CNS lymphoma collaborative group report.
All were due to Non-Hodgkin's lymphoma out of which 3 were due to neurolymphomatosis and 3 were due to leptomeningeal involvement.
Neurolymphomatosis (NL)(16) seen in three of our patients is characterized by infiltration of malignant lymphocytes into the peripheral nervous system particularly the cranial nerves, spinal nerve roots, brachial/lumbar plexus, and/or peripheral nerves.
For the suspected case of neurolymphomatosis, patient 8, a dual color probe for the 3q27 (BCL6) locus was used for enumeration of chromosome 3 and a dual color MALT1 (18q21) break apart probe for that locus to assess translocation.
This case was suspected to be neurolymphomatosis by light microscopy (Figure 1, I) and the combination of immunoreactivity for both CD5 (Figure 1, J) and bcl-2, but all attempts to prove clonality by polymerase chain reaction-based gene rearrangement were negative.