NLGN2

(redirected from neuroligin-2)

NLGN2

A gene on chromosome 17p13.1 that encodes neuroligin 2, a neuronal cell surface protein involved in cell–cell interactions (e.g., in neurons and in other types of cells, such as Langerhans beta cells), which forms intercellular junctions by binding to beta-neurexins. It may play role in forming or maintaining synaptic junctions.
References in periodicals archive ?
Gephyrin, in turn, is recruited to and stabilised at the synapse by the adhesion protein neuroligin-2 (NL2).
Activity-Dependent Validation of Excitatory versus Inhibitory Synapses by Neuroligin-1 versus Neuroligin-2.
Neuroligin-1 is a specific CAM for excitatory (glutamatergic) synapses, while neuroligin-2 is a specific CAM for inhibitory (GABAergic) synapses.