In 35 chapters, toxicologists, pathologists, and other scientists from North America and Europe explain the fundamentals of neurobiology, including neuroanatomy, behavioral systems and cognitive assessments, the effects of aging on brain structure and function, and issues relevant to study design; methodology, including neurohistology
, practical markers for neurotoxicity, stereology, and the processing and evaluation of peripheral nerves, muscle, and cerebrospinal fluid; practices for evaluation of the nervous system and ophthalmic and olfactory systems; and applications, such as in veterinary and medical practice and diagnostic neuropathology, as well as regulatory issues, reports, and preparation of personnel.
Topics covered are light-microscopic neurohistology
; electron-microscopic neurohistology
; the skull, meninges, and spinal cord; gross and sectional anatomy of the brain; and an introduction to brain imaging and MRIs.