neurognathostomiasis

neurognathostomiasis

(noor″ō-(g)nă-thos″tŏ-mī′ă-sĭs, nūr″) [ neuro- + gnathostomiasis]
Infection of the central nervous system by parasitic nematodes of the genus Gnathostoma.
References in periodicals archive ?
Neurognathostomiasis, a neglected neglected parasitosis of the central nervous system.
Neurognathostomiasis, a neglected parasitosis of the central nervous system.
Immunoblot diagnostic test for neurognathostomiasis.
Although gnathostomiasis is endemic to Asia and Latin America, almost all neurognathostomiasis cases are reported from Thailand.
We found 24 reports describing a total of 248 patients with neurognathostomiasis published in English-language literature.
With the advance of high-resolution neuroimaging, the parasitic tracks of Gnathostoma could be demonstrated on magnetic resonance imaging (MRI), aiding the diagnosis of neurognathostomiasis in the absence of worm recovery (11).
Most (241/248) identified cases of neurognathostomiasis reported in the English-language literature were from Thailand.
The first case of neurognathostomiasis in a traveler was reported in 2003 (19).
The hallmark sign of neurognathostomiasis is the evidence of multiple hemorrhagic tracks; these tracks have been documented throughout the spinal cord and brain tissue by postmortem examination (9), as well as through neuroimaging (31).
The main clinical syndromes of neurognathostomiasis are radiculomyelitis/ radiculomyeloencephalitis, meningitis/meningoencephalitis, and subarachnoid and intracerebral hemorrhage (Table 1).
However, in the largest published series of neurognathostomiasis in 162 patients, only 11 (7%) had a history of cutaneous lesions (10).
Neuroimaging of 11 patients with neurognathostomiasis was reported in English-language literature.