Neurogenetics of dopaminergic receptor supersensitivity in activation of brain reward circuitry and relapse: proposing "deprivation-amplification relapse therapy" (DART).
Following an introduction to basic concepts for clinicians, information is provided about procedures for CSF analysis, neurochemical examinations, evaluation of biopsies, and clinical applications of neuroimmunology, microbiology, virology, and
neurogenetic tests.
The group included the patients who were on hospitalization in neurological department and patients registered on the dispensary account on CMT in advisory polyclinic of Clinical Hospital No51 FMBA (Zheleznogorsk, RF), the patients passing hospitalization in neurologic department of Urban Hospital No5 (Krasnoyarsk, RF), and also the patients found in the Neurologic Centre of Epileptology,
Neurogenetic and Brain Researches of University Clinic.
Huntington's disease (HD) is a progressive
neurogenetic disorder that has a 50% inheritance rate.
The inverted
neurogenetic gradient of the mammalian isocortex: development and evolution.
Two broad research themes: a Genetic & Molecular Medicine research program with a focus on personalized medicine, gene therapy, stem cell research, vaccine development; and a Women and Children's Health research program with a focus on maternal foetal medicine and the
neurogenetic disorders of the newborn.
The SVZ is the adult brain region with the highest
neurogenetic rate, from which NSCs have been first isolated and characterized for their ability to give rise to nonneural cells (1).
The strategy is to take advantage of the earlier ages to activate, promote, and optimize neurobehavioral structures and processes which would remain underdeveloped due to adverse
neurogenetic effects on the ontogenesis.
The research inclusion criteria specified that, based on parental interview and questionnaire, the child showed no indication in developmental or medical history of brain injury or disease, intellectual deficiency, primary language or motor disorders, autism spectrum or other pervasive developmental disorder, diagnosis of severe social emotional disturbance, or
neurogenetic disorder associated with abnormal development.
Other common inherited genetic diseases are some muscle diseases,
neurogenetic disorders and inherited deafness, said Dr Leonidas Fylaktou, Head of the Molecular Genetics, Function and Therapy Department at the Institute of Neurology and Genetics.
We have established two broad research themes: a genetic and molecular medicine research programme with a focus on personalised medicine, gene therapy for cancer and stem cell research; and a women and children's health research programme with a focus on maternal fetal medicine and
neurogenetic disorders of the newborn.
The Lili Claire Foundation provides support services to children living with
neurogenetic conditions such as Down Syndrome and autism.
