The prevalence of adult neurogenesis
in humans and primates is an area of active discussion in the field and more research is needed to determine whether the process of stem cell generation observed in the mouse pertains to other mammals too.
was demonstrated by detecting an increased number of cells containing Ki67, a marker of dividing cells, scored by scientists blinded to the treatment groups.
 Our results showed that EPO has a significant effect on neurogenesis
in the granular zone of dentate gyrus in Alzheimer's rats.
in the hippocampus is critical to learning and memory, but how conditions such as Alzheimer's affect this process isn't well understood.
It was here where they discovered that neurogenesis
persists even among the elderly, and does not stop in adolescence: 'We found there were on the other of thousands of neuroprogenitor cells and immature neutrons both in the youngest and the oldest people analyzed.'
These results indicate that GLe can promote adult neurogenesis
in the DG of the hippocampus and that increases of BDNF and TrkB expressions in the DG following GLe treatment might be closely associated with neurogenic effects of GLe.
Does Not Underlie Cognitive Improvement after Cell Implantation.
In his book, Cortright points to research showing that neurogenesis
is "the most important biomarker for brain health most people never heard of." While a low rate of neurogenesis
is linked with mental disorders such as anxiety, depression, stress, and cognitive deficits, a high rate of neurogenesis
has only positive effects--lowered stress, anxiety and depression, plus enhanced cognitive abilities including faster learning and better problem-solving skills.
The level of stress response was found to be inversely related to the level of neurogenesis
in the hippocampus.
TJZL184, a monoacylglycerol lipase inhibitor, exhibited antidepressant effects by enhancing adult neurogenesis
and long-term synaptic plasticity in the dentate gyrus of the hippocampus .
As a result, a number of naturally occurring dietary antioxidants have been identified with properties that support neurogenesis
. The role of antioxidants has also been implicated in the functional outcomes in ageing and neurodegenerative disorders and their protective role is clearly linked to such outcomes in the abovementioned studies.
occurs, several types of progenitor cells are observed.