neurofibrosarcoma

/neu·ro·fi·bro·sar·co·ma/ (-fi″bro-sahr-ko´mah) a malignant type of schwannoma superficially resembling a fibrosarcoma, sometimes occurring in association with neurofibromatosis that is undergoing malignant transformation.

malignant peripheral nerve sheath tumour

A poorly understood malignancy, presumably of Schwann cell origin, which is thought to arise from the neural crest. It is the most common malignancy of peripheral nerves, and represents 5 to 10% of all soft-tissue tumours. It occurs in the lower extremities in relatively young patients (age 20 to 50). Half of cases occur in patients with neurofibromatosis type 1, in which the male:female ratio is 4:1; 2/3 of MPNSTs arise from neurofibromas, 1/3 arise de novo. Origin from pre-existing schwannomas, ganglioneuromas or phaeochromocytomas are rare; 10% arise in a background of therapeutic radiation.

Management
Wide local excision; radiation and chemotherapy have been used with varying degrees of failure.

neurofibrosarcoma

See NEUROSARCOMA.

neurofibrosarcoma

a malignant tumor originating from Schwann cells of the peripheral nervous system and seen most commonly in cattle.

Mentioned in ?

neurosarcoma

References in periodicals archive ?

Case 1 Case 2 Sex Male Female Breed Mixed Mixed Age 12 years 10 years- Neoplasms of Skin tumors in the Inguinal near the vulva the location pelvic member, knee region Neoplasia type Neurofibrosarcoma Solid mammary carcinoma Type of surgery Subdermal tube near the Subdermal tube near the flank region.

The use of tubular subdermal and axial flaps in the correction of four cases of extensive lesions/Retalhos tubulares subdermicos e axiais utilizados em quatro casos de correcao de lesoes extensa

Neurofibrosarcoma is a rare neoplasm that may arise independently or in association with neurofibromatosis; it is one of the most lethal diseases.

Neurofibromatosis type I: a case report and review of the literature

6,7,12) Other reported STSs in birds include leiomyosarcoma, (9,12) rhabdomyosarcoma, (9,11,12) myxosarcoma, (10,14) liposarcoma, (12,15) neurofibrosarcoma, (16,17) and histiocytic sarcoma.

Pelvic limb amputation for the treatment of a soft-tissue sarcoma of the tibiotarso-tarsometatarsal joint in a blue-and-gold macaw (Ara ararauna)

1,2) Sarcomas of the elderly are leiomyosarcoma, angiosarcoma, spindle cell sarcoma, alveolar soft part sarcoma, fibrosarcoma, neurofibrosarcoma, and mixed mesodermal tumors of the vagina.

Spindle cell sarcoma of vagina--a case report

In such patients, the incidence of malignant transformation to neurofibrosarcoma is increased.

Deep-lobe parotid tumor presenting in the parapharyngeal space

The tumour, known as a Neurofibrosarcoma, makes up just one per cent of all cancers, and it grew quickly, resulting in Paul having a 4lb tumour removed from his abdominal area.

Cancer patient beats fundraising target

Chromosomes 17 and 11 involved in marker formation in neurofibrosarcoma in von Recklinghausen disease: a cytogenetic and in situ hybridization study.

An Unusual Cerebellopontine Angle Tumor

24-41) In Canada geese in particular, neurofibrosarcoma, lipoma, liposarcoma, fibroma, and spindle cell sarcoma have all been reported.

Infiltrative spinal lipoma in a Canada goose (Branta canadensis)

Differential diagnosis of Castleman's disease Mediastinum Head and neck Hypervascular metastasis Carcinoma of the thyroid Leiomyosarcoma Cat scratch fever Lymphoma Epstein-Barr virus Mediastinitis Hodgkin's disease Medullary carcinoma Human immunodeficiency of the thyroid virus infection Neurofibrosarcoma Infectious lymphadenitis Parathyroid adenoma Lymphoma Substernal goiter Metastatic disease Thymoma Paraganglioma Parathyroid adenoma Schwannoma

Castleman's disease: three case reports and a review of the literature

12) Cases of multicentric neurofibrosarcoma have been previously described in Canada geese (Branta canadensis).

Peripheral nerve sheath tumor in a subadult golden eagle (Aquila chrysaetos)

The type of tumour, known as a neurofibrosarcoma, makes up just 1per cent of all cancers.

Now it's my turn to help the hospital; CHARITY BALL: Young man in cancer op organises pounds 1,000 fundraiser

Malignant schwannoma--also known as neurogenic sarcoma, neurofibrosarcoma, malignant neurofibroma, and recently renamed malignant peripheral nerve sheath tumor--is a rare form of cancer that accounts for 5% of all soft-tissue tumors and affects 0.

Recurrent malignant schwannoma of the parapharyngeal space in neurofibromatosis type 1