neurofibrillary degeneration

neu·ro·fi·bril·la·ry de·gen·er·a·tion

formation of coarse, argentophilic, intracytoplasmic fibers, often in complex tangles within intracranial nerve cells.
See also: Alzheimer disease.
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References in periodicals archive ?
It is one of more than 20 different neurodegenerative disorders characterized by neurofibrillary degeneration and tau inclusions as a predominant central nervous system lesion.
Exposure to high levels of aluminium (Al) leads to neurofibrillary degeneration and that Al concentration is increased in degenerating neurons in Alzheimer's disease (AD).
Intraventricular administration of Al-maltolate to rabbits developed widespread neurofibrillary degeneration involving pyramidal neurons of the isocortex and allocortex, projection neurons of the diencephalon, and nerve cells of the brain stem and spinal cord (37).
We also focused on the similarities and dissimilarities between Al-induced neurofibrillary degeneration and paired helical filaments from AD and the prevalence of AD.
Experimental production of neurofibrillary degeneration.
Brain aluminium distribution in Alzheimer's disease and experimental neurofibrillary degeneration.
Experimental models of metal-induced neurofibrillary degeneration.
Partial reversal of aluminium-induced neurofibrillary degeneration by desferrioxamine in adult male rabbits.
Tau immunoreactivity associated with aluminium maltolate induced neurofibrillary degeneration in rabbits.
Aluminium-induced neurofibrillary degeneration affects a subset of neurons in rabbit cerebral cortex, basal forebrain and upper brainstem.
Kinases and phosphatases and tau sites involved in Alzheimer neurofibrillary degeneration.