neurofibrillary degeneration

neu·ro·fi·bril·la·ry de·gen·er·a·tion

formation of coarse, argentophilic, intracytoplasmic fibers, often in complex tangles within intracranial nerve cells.
See also: Alzheimer disease.
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References in periodicals archive ?
Implications for neurofibrillary degeneration in Alzheimer's disease.
Biochemistry and cell biology of tau protein in neurofibrillary degeneration. Cold Spring Harb Perspect Med 2012;2:a006247.
Abnormal hyperphosphorylation of tau: Sites, regulation, and molecular mechanism of neurofibrillary degeneration. J Alzheimers Dis 2013;33 Suppl 1:S123-39.
Mesulam, "Locus coeruleus neurofibrillary degeneration in aging, mild cognitive impairment and early Alzheimer's disease," Neurobiology of Aging, vol.
Intraventricular administration of Al-maltolate to rabbits developed widespread neurofibrillary degeneration involving pyramidal neurons of the isocortex and allocortex, projection neurons of the diencephalon, and nerve cells of the brain stem and spinal cord (37).
We also focused on the similarities and dissimilarities between Al-induced neurofibrillary degeneration and paired helical filaments from AD and the prevalence of AD.
Experimental production of neurofibrillary degeneration. J Neuropath Exp Neur 1965; 24 : 187-99.
Brain aluminium distribution in Alzheimer's disease and experimental neurofibrillary degeneration. Science 1973; 180 : 511-3.
Partial reversal of aluminium-induced neurofibrillary degeneration by desferrioxamine in adult male rabbits.
Tau immunoreactivity associated with aluminium maltolate induced neurofibrillary degeneration in rabbits.
Kinases and phosphatases and tau sites involved in Alzheimer neurofibrillary degeneration. Eur J Neurosci 2007;25: 59-68.