The day 10 neuroepithelium
was consistent with the mouse neuroectodermal cell line NE-4C after RA treatment.
narrows and lengthens, a process referred to as convergent extension (Figure 3(a)), in which the polarized cells which form the neuroepithelial plate converge towards the midline, elongate anteroposteriorly, and then intercalate [215, 225].
Markers such as SOX2 and SALL4 (Figure 10, A and B) are strongly expressed by immature neuroepithelium
but are weaker or absent in well-differentiated neural areas.
The most characteristic histopathology of vestibular neuritis in the human temporal bone is degeneration of the superior vestibular nerve and vestibular ganglion with variable involvement of the neuroepithelium
of the end organs and a deficiency in the population of the nerve fibres and microscopic findings of myelin degeneration.
The incidence of protozoal and helminthic infestations of the central nervous system (CNS) is less than 1%, but these infestations tend to follow a fatal course.1 The free-living amoebae Naeglaeria fowleri (NF) cause extremely rare and sporadic CNS infections termed as primary amoebic meningoencephalitis (PAM).2 It is an acute, fulminant, rapidly fatal disease that occurs generally in previously healthy children and young adults with a history of swimming and diving and other recreational activities in fresh water and contaminated swimming pools.3 The portal of entry is via the olfactory mucosa and neuroepithelium
. Incubation period is 3-8 days with acute and rapidly fatal course.
Using isolated tissue from the nervous system (i.e., neuroepithelium
) of second-trimester fetuses, the investigators demonstrated that ethanol suppressed the expression of four miRNAs--miR-9, miR-21, miR-153, and miR335--in fetal neural stem cells (NSCs) and neural progenitor cells (NPCs).
Another potential sequalae of low CSF glucose is direct damage to the cochlea neuroepithelium
The complex cellular arrangement of the vertebrate central nervous system, including the neuroretina, largely arises from the apparently undifferentiated, pseudostratified neuroepithelium
. During early embryonic development, neuroepithelial cells undergo sequential proliferation and differentiation to give rise to neurons and glial cells.
They also found that PD exposure caused necrosis and apoptosis in the olfactory neuroepithelium
and activation of caspase 3, a protein that plays a role in cell death, in axons of olfactory nerve bundles.
Aminoglycoside ototoxicity targets the sensory neuroepithelium
of the cochlea.
First documented in 1858 by Wallmann, the cyst develops from the neuroepithelium
of the diencephalic roof and usually implants into the third ventricle.
Subsequently, it invades the central nervous system through the olfactory neuroepithelium
and causes a fatal infection that clinically resembles acute bacterial meningitis.