neuroendocrine tumor


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Related to neuroendocrine tumor: Carcinoid tumor, Neuroendocrine cancer

neuroendocrine tumor

Neuropathology A neoplasm with a characteristic morphology, often composed of clusters and trabecular sheets of round 'blue cells', granular chromatin, and an attenuated rim of poorly demarcated cytoplasm Examples Carcinoids, small–'oat' cell carcinomas, medullary carcinoma of thyroid, Merkel cell tumor, cutaneous neuroendocrine CA, pancreatic islet cell tumors, pheochromocytoma. See Neurosecretory granules.
References in periodicals archive ?
The distinction of primary from metastatic neuroendocrine tumor is critical to avoid misdiagnosis and unnecessary surgical and medical therapy in the latter.
Differential diagnosis of solid pseudo-papillary tumor of pancreas includes pancreatic neuroendocrine tumors, pancreatoblastoma, acinar cell carcinoma and pancreatic pseudocyst3,18.
In the WHO classification, neuroendocrine tumors have been defined as those in which one or more neuroendocrine markers, such as neuro specific enolase, chromogranin A, and/or synaptophysin, are expressed in at least 50% of cancer cells.
Background: The optimal surgical management of nonfunctional pancreatic neuroendocrine tumors (NF-PNETs) is still controversial.
The immunohistochemical reactions confirmed the presence of a neuroendocrine tumor positive for Chromogranin (Figures 15 and 16), Synaptophysin, NSE (Figure 17) and CD56.
In addition to the surveillance previously recommended for the potential association of GLP-1--based therapy and pancreatic cancer risk, the current data imply that surveillance for a possible increased risk of pancreatic neuroendocrine tumors is warranted.
Treatment ofpoorly differenciated neuroendocrine tumors with etoposide and cisplatin.
Many imaging specialists would be more likely to bring attention to subtle areas of increased tracer uptake when there is clinical and/or laboratory evidence of a neuroendocrine tumor, as in this case.
Surgery in malignant pancreatic neuroendocrine tumors.

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