neuroendocrine neoplasm

neuroendocrine neoplasm (pancreas)

A general term for tumours (e.g., glucagonomas, insulinomas, etc.), which arise in the endocrine cells of the pancreas.

Prognostic indicators
Depends on TMN stage when diagnosed; mitotic rate and MIB-1/K1-67 labelling index, which determine tumour grade; invasion of large vessels; expression of cytokeratin 19; tumour necrosis.
References in periodicals archive ?
Small cell carcinoma of the bladder is a rare, aggressive, poorly differentiated neuroendocrine neoplasm accounting for only 0.
Optimizing the surgical effort in patients with advanced neuroendocrine neoplasm hepatic metastases: a critical analysis of 40 patients treated by hepatic resection and cryoablation.
In pancreatic endocrine tumors, curative resection improved the survival of many patients with non-functioning neuroendocrine neoplasm of the pancreas.
Biopsies were consistent with rectal small-cell carcinoma characterized as a poorly differentiated neuroendocrine neoplasm (Figure 2).
H&E staining demonstrated a neuroendocrine neoplasm (Fig.
The final histologic evaluation of the excised biopsy specimen yielded a diagnosis of a well-differentiated neuroendocrine neoplasm (typical carcinoid).
The dyscohesive pattern of the tumor cells generated the differential considerations of a neuroendocrine neoplasm, a lymphoproliferative disorder, and melanoma.
Multicentric small cell neuroendocrine neoplasm of the renal pelvis and ureter with concomitant focal high-grade urothelial carcinoma of the ureter: a case report.
12) Nonetheless, close scrutiny of the neoplasm reveals cords, festoons, and gyriform patterns of tumor cell arrangement, thereby raising the possibility of a neuroendocrine neoplasm.
The biopsy specimen yielded what was initially interpreted as a neuroendocrine neoplasm suggestive of a poorly differentiated neuroendocrine carcinoma of the larynx; staining revealed that the specimen was positive for cytokeratin, carcinoembryonic antigen, chromogranin, synaptophysin, and calcitonin.
4) The term neuroendocrine neoplasm has been accepted as general nomenclature instead of carcinoid because carcinoid does not convey the malignant nature of the tumors and can be confused with carcinoid syndrome.

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