neuroendocrine neoplasm

neuroendocrine neoplasm (pancreas)

A general term for tumours (e.g., glucagonomas, insulinomas, etc.), which arise in the endocrine cells of the pancreas.

Prognostic indicators
Depends on TMN stage when diagnosed; mitotic rate and MIB-1/K1-67 labelling index, which determine tumour grade; invasion of large vessels; expression of cytokeratin 19; tumour necrosis.
References in periodicals archive ?
Disseminated Pancreatic Neuroendocrine Neoplasm (NEN) with an Uncommon Localisation in the Central Nervous System.
Caruso, "Role of PD-L1 expression as a biomarker for GEP neuroendocrine neoplasm grading," Cell Death & Disease, vol.
TABLE 1: The clinicopathological characteristics of 68 colorectal neuroendocrine neoplasm patients.
Morris, "Optimizing the surgical effort in patients with advanced neuroendocrine neoplasm hepatic metastases: A critical analysis of 40 patients treated by hepatic resection and cryoablation," American Journal of Clinical Oncology: Cancer Clinical Trials, vol.
Small cell carcinoma of the bladder is a rare, aggressive, poorly differentiated neuroendocrine neoplasm accounting for only 0.3-0.7% of all bladder tumors.
Biopsies were consistent with rectal small-cell carcinoma characterized as a poorly differentiated neuroendocrine neoplasm (Figure 2).
H&E staining demonstrated a neuroendocrine neoplasm (Fig.
The histologic differential diagnosis of malignant melanoma of the esophagus is broad and includes lymphoma, poorly differentiated carcinoma (either squamous or adenocarcinoma), a high-grade neuroendocrine neoplasm, and possibly a metastasis or direct extension of a primary tumor elsewhere.
In pancreatic endocrine tumors, curative resection improved the survival of many patients with non-functioning neuroendocrine neoplasm of the pancreas.
Abbreviation ADC: Adenocarcinoma NEN: Neuroendocrine neoplasm NET: Neuroendocrine tumor NEC: Neuroendocrine carcinoma MANEC: Mixed adenoneuroendocrine carcinoma MiNEN: Mixed neuroendocrine-nonneuroendocrine carcinoma.
The dyscohesive pattern of the tumor cells generated the differential considerations of a neuroendocrine neoplasm, a lymphoproliferative disorder, and melanoma.
The biopsy specimen yielded what was initially interpreted as a neuroendocrine neoplasm suggestive of a poorly differentiated neuroendocrine carcinoma of the larynx; staining revealed that the specimen was positive for cytokeratin, carcinoembryonic antigen, chromogranin, synaptophysin, and calcitonin.

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