Siew said the team developed its experiment based on the model of Huntington's disease, a neurodegenerative disorder
that causes progressive deterioration of motor and cognitive functions, using mice to observe their 14-week life cycle under the effects of the disease.
MS is a chronic neuroinflammatory and neurodegenerative disorder
that affects the brain and spinal cord.
BMS will license its experimental neurodegenerative disorder
drug, BMS-986168, to Biogen as a treatment for progressive supranuclear palsy, a degenerative disease involving the gradual deterioration and death of specific volumes of the brain.
A trial conducted at Massachusetts General Hospital has uncovered a benefit for creatine in delaying the symptoms of the inherited neurodegenerative disorder
known as Huntington disease in asymptomatic adults.*
Cyanobacteria produce a neurotoxin thought to be the cause of a neurodegenerative disorder
Estimates vary, but research suggests that anywhere from 80 to 100 percent eventually get a neurodegenerative disorder
A recent study indicates that Vitaline CoQ10 may be associated with signs of clinical improvement on several quality of life scales for patients with Multiple System Atrophy (MSA), a progressive neurodegenerative disorder
that causes loss of motor function (muscle coordination, tremor and rigidity, slurred speech) and other symptoms.
HD is a late-onset, autosomal dominant neurodegenerative disorder
characterised by progressive movement impairment, affective disturbance and cognitive dysfunction.
The company has also generated pre-clinical efficacy data with its ReN005 stem cell therapy for Huntington's disease, a rare, genetic and fatal neurodegenerative disorder
which affects around 1 in 100,000 people.
"I've been in the neurodegenerative disorder
field for quite a while, says Mattson.
The herbicides and pesticides many people trust enough to spray on their gardens and crops have been increasingly linked to the onset of Parkinson's Disease (PD), a neurodegenerative disorder
that turns the simplest movement into a battle between the brain and the nerves.
Parkinson's disease is the second most common neurodegenerative disorder
after Alzheimer's disease.