Neurocutaneous melanosis | definition of neurocutaneous melanosis by Medical dictionary
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neu·ro·cu·ta·ne·ous mel·a·no·sis [MIM*249400]
cutaneous giant pigmented nevi associated with melanosis of the leptomeninges; melanomas may develop in the skin or meninges.
A rare disorder marked by the presence of multiple or large pigmented nevi on the skin and in the leptomeninges of the central nervous system.
References in periodicals archive
: definition and review of the literature.
What was less appreciated in the past was the incidence of neurocutaneous melanosis
in children with large congenital nevi.
Large congenital melanocytic nevi with multiple small satellite lesions carry higher risk for neurocutaneous melanosis
, as well as melanoma.