In infancy and childhood, inborn errors of metabolism and developmental disorders such as neuronal migration anomalies and neurocutaneous
syndromes predominate as identifiable causes.
The differential diagnosis includes: MRI sequence artifact seen on some but not all sequences, normal or abnormal surface veins, neurocutaneous
melanosis or meningioangiomatosis.
We report a rare case of malignant meningeal melanomatosis with associated neurocutaneous
melanomatosis presenting as such.
Hypomelanosis of Ito associated with benign tumours and chromosomal abnormalities: a neurocutaneous
Neurology Part 1 -- Weakness, Hypotonia, Ataxia, Congenital Malformations of the Brain, Degenerative Disorders, Neurocutaneous
Tuberous sclerosis and von Hippel Lindau (vHL) disease belong to the phakomatoses, a group of neurocutaneous
disorders that may have cysts in the viscera.
Included are pseudoneoplastic mimics of epithelial tumors, imitators of regressing and regressed melanocytic neoplasms, pseudoneoplastic mesenchymal lesions, pseudoneoplastic neurocutaneous
rests and ectopias, and pseudoneoplastic lymphoreticular infiltrates.
The skin must be examined for features of neurocutaneous
In approximately 75% of the patients, seizures are related to cortical malformations, perinatal events, neurocutaneous
syndromes (tuberosclerosis, Sturge Weber .
Tuberous sclerosis is one of the neurocutaneous
diseases involving skin, brain, kidney and heart abnormalities in the form of abnormal tubers.
As these lesions were suggestive of a neurocutaneous
syndrome, magnetic resonance imaging of the brain was performed to identify any additional lesions.
Cortical dysplasia, genetic abnormalities and neurocutaneous