neuroaxonal dystrophy

neu·ro·ax·o·nal dys·tro·phy

a rare disorder that begins in the second year of life and is relentlessly progressive; clinically characterized initially by walking difficulties, weakness, and areflexia, later followed by corticospinal and pseudobulbar findings, blindness, loss of pain appreciation, and mental deterioration; pathologically, eosinophilic spheroids of swollen axoplasm are found in various central nuclei; autosomal recessive inheritance.

neuroaxonal dystrophy

a degenerative disease believed to be inherited in several breeds of dogs and cats. Progressive signs of cerebellar dysfunction with ataxia, hypermetria, proprioceptive deficits, incoordination and tremors develop from an early age. It has been reported in Rottweilers, Collie sheepdogs and Bull mastiffs.

Mentioned in ?

References in periodicals archive ?

Some of the NBIA disorders include aceruloplasminemia, fatty acid hydroxylase-associated neurodegeneration, infantile neuroaxonal dystrophy, Kufor-Rakeb syndrome, neuroaxonal dystrophy, neuroferritinopathy.

Eye of tiger sign: clinical phenotypes

Pope Benedict also blessed 18-month-old Alexander Frame, who has an incurable genetic disorder called neuroaxonal dystrophy.

MY HERO THE POPE; Cancer lad's joy at Benedict blessing

New topics include infantile neuroaxonal dystrophy, neuronal migration disorders, meningococcal vaccines, pneumococcal meningitis, rivastigmine, Pervasive Developmental Disorders, and TORCH Disorders.

The encyclopedia of the brain and brain disorders, 3d ed

The work, supported by the children's medical research charity WellChild, has also uncovered a genetic mutation, which causes Infantile Neuroaxonal Dystrophy that slowly degenerates the nerves throughout a child's body and ultimately results in death.

South City News: Genetic find gives kids hope; EDGBASTON: Scientific discovery could help fight fatal disease

He is suffering from rare condition called neuroaxonal dystrophy for which there is no cure.