neuralgic amyotrophy


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neu·ral·gic a·my·ot·ro·phy

a neurologic disorder, of unknown cause, characterized by the sudden onset of severe pain, usually about the shoulder and often beginning at night, soon followed by weakness and wasting of various forequarter muscles, particularly shoulder girdle muscles; both sporadic and familial in occurrence with the former much more common; often preceded by some antecedent event, such as an upper respiratory infection, hospitalization, vaccination, or nonspecific trauma; usually attributed to a brachial plexus lesion, because the nerve fibers involved are most often derived from the upper trunk.

neuralgic amyotrophy

[noo͡ral′jik ā′mīot′rəfē]
a brachial plexus disorder characterized by sudden pain and muscle weakness in the upper limbs and sometimes by muscular wasting or atrophy. The cause is unknown. Also called Parsonage-Turner syndrome.
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Neuralgic amyotrophy

shoulder girdle syndrome

A condition evoked by upregulation of the sympathetic nervous system.
 
Aetiology
Contusions, fractures, neurovascular injuries.
 
Clinical findings
Acute searing pain, marked muscle-weakness, vasomotor lability, oedema, osteoporosis and, with time, wasting of the shoulder girdle and upper arm.
 
DiffDx
• Acute phase—Frozen shoulder, calcific tendonitis or arthritis.
• Chronic phase—Rotator cuff tears, nerve root compression.

neu·ral·gic a·my·ot·ro·phy

(nūr-al'jik ā'mī-ot'rŏ-fē)
A neurologic disorder of unknown cause, characterized by the sudden onset of severe pain, usually about the shoulder and often beginning at night, soon followed by weakness and wasting of various forequarter muscles, particularly shoulder girdle muscles; both sporadic and familial in occurrence with the former much more common; often preceded by some antecedent event, such as an upper respiratory infection, hospitalization, vaccination, or nonspecific trauma; usually attributed to a brachial plexus lesion, because the nerve fibers involved are most often derived from the upper trunk, but actually multiple proximal mononeuropathies.
Synonym(s): shoulder-girdle syndrome.
References in periodicals archive ?
8 34/F/1 Intercostal allodynia Controlled with amitriptyline Post-thoracotomy syndrome 9 83/F/3 Paraesthesia and Persistent weakness left arm Brachial plexopathy at fracture level 10 53/M/3 Pain in wrist with Persistent difficulty making fist Ulnar axonopathy at surgical site 11 69/M/3 Weakness of wrist Improving extension (day 10) Post-viral neuralgic amyotrophy.
Neuralgic amyotrophy associated with hepatitis E virus.
Neuralgic amyotrophy as the primary cause of shoulder painin a patient with rotator cuff tear.
Evidence of a founder effect and refinement of the hereditary neuralgic amyotrophy (HNA) locus on 17q25 in American families.
reported a case of HEV genotype 3-induced neuralgic amyotrophy in which HEV RNA was detected in the serum of patients with neurologic signs and symptoms (14), and we recently detected HEV RNA in the cerebrospinal fluid (CSF) of a kidney-transplant recipient with chronic HEV infection and neurologic signs and symptoms (15).