neural crest cell


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neural crest cell

Embryonic cells of the neuron-glia lineage that form along the ridges (neural folds) of the neural plate and that migrate into the developing organism to produce a variety of tissues. The migratory ability of these embryonic epithelial cells is similar to the motility of mesenchyme cells; this has led neural crest cells to be called mesectodermal cells. In the neural lineage, neural crest cells give rise to the dorsal root ganglia, the placodes that will develop into the olfactory and auditory sensory organs, the pituitary gland, the peripheral autonomic nervous system, and the neurenteric and APUD cells. In the glial lineage, neural crest cells give rise to Schwann cells and other peripheral satellite cells. In addition, neural crest cells of the cranial region give rise to certain facial connective tissue, including the bones of the nasal cavities, the roof of the mouth, and the sella turcica.
See also: cell
References in periodicals archive ?
The wandering cells are neural crest cells, which appear early in development in vertebrate embryos.
As Wilkins tells it, he was photocopying research papers about neural crest cells for a book he is writing on the human face.
Alcohol's deleterious effects on these cranial neural crest cells during a narrow period of embryonic development most likely cause the characteristic facial features observed in people with FAS.
During embryonic development, the facial cartilage and bone responsible for these craniofacial features (as well as certain central nervous system cells) are derived from a subset of embryonic cells called cranial neural crest cells.
This soft tissue neoplasm is thought to derive from neural crest cells.
Xslug has been demonstrated to play a pivotal role in both the induction and the subsequent migration of neural crest cells in Xenopus (Carl et al.
Moreover, although our results suggest that neural crest derivatives may be highly sensitive and excellent markers of the disruptive actions of environmental estrogens, these toxicants appear more likely to interfere with factors that regulate the later differentiation of neural crest cells rather than those that control their early induction.
As with other paragangliomas described outside the distribution of paraganglionic tissue, our case can best be explained by the currently incompletely understood migration patterns of the widely dispersed neural crest cells.
15 /PRNewswire/ -- Cylene Pharmaceuticals today announced the initiation of a Phase II clinical trial of quarfloxin (CX-3543) in patients with carcinoid/neuroendocrine tumors (C/NET), which are malignant cancers arising from neural crest cells.
Vertebrates have three types of embryonic tissue not present in invertebrates: neural crest cells, ectodermic placodes, and a modified paraxial mesoderm.