Immunohistochemistry (IHC), real-time polymerase chain reaction (PCR), and Western blotting were used to detect the expression of Nestin
mRNA and protein in the subventricular zone (SVZ) of the brain.
3 Immunohistochemically, epithelium shows positive expressions of cytokeratins (CK), especially CK5, CK14, and CK19, and mesenchymal tumor cells show positive expression of nestin
In an initial study of gliomagenesis, (65) the same mouse employed to drive expression of mutant IDH via the Nestin
promoter exhibited a perinatal lethal phenotype characterized by cerebral hemorrhage.
The Minister of Road Transport & Highways Shri Nitin Gadkari unveiled the logo for HIGHWAY VILLAGE and HIGHWAY NESTin
New Delhi today.
cells that could still be radial glia as there is some nestin
expression even after 8 weeks of development (Lyck et al.
positively regulates the Wnt/beta-catenin pathway and the proliferation, survival and invasiveness of breast cancer stem cells.
01), relative to the control group, while analysis indicated that the mean percentage of Nestin
positive cells significantly increased in the treated group in comparison to control group (p<0.
Berberine attenuated cancer sternness markers CD133, [beta]-catenin, n-myc, sox2, notch2 and nestin
Axelsson C, Nestin
J, Svensson L, Axelsson AB, Herlitz J.
Rats with induced HIBI were given FGF2, and then nestin
and growth-associated protein-43 (GAP-43) expression in the brain and cognitive functioning were investigated.
Keilholz, "Expression of the stem cell marker nestin
in peripheral blood of patients with melanoma," British Journal of Dermatology, vol.
A unique feature of C6 culture is that, exactly like a GBM tumor, it contains a subculture of cancer stem cells that express CD133 and nestin
, which are widely used markers for brain CSCs ; therefore we choose this cell line for our investigations.