The toxin produced by the tick interrupts the sodium flux across axonal membranes in selected locations such as the nodes of Ranvier and nerve terminals
Motoneuron-derived agrin is secreted from nerve terminals
into the synaptic cleft and leads to clustering and synthesis of postsynaptic AChRs through activation of the postsynaptic LRP4-MuSK-Dok-7 complex.
They called this previously undescribed class of high-threshold mechanoreceptors (HTMRs) circ-HTMRs, due to the unusual nerve terminals
these neurons made in skin.
3]H]-acetylcholine release from rat motor nerve terminals
Amino glycosides including streptomycin have been found to cause modulation of the release of excitatory neurotransmitters from primary afferent nerve terminals
Other research, such as that led by Charles Liberman, a professor of otology and lanyngology at Harvard Medical School, is looking into regenerating the damaged auditory nerve terminals
, reestablishing the broken links to hair cells.
After exocytic fusion, synaptic vesicles are retrieved by endocytosis into nerve terminals
, refilled with neurotransmitter and reused (Fig.
Capsaicin-sensitive sensory nerve terminals
with local and systemic efferent functions: facts and scopes of an unorthodox neuroregulatory mechanism.
Urothelial-released ATP is also inhibited by botulinum toxin A, suggesting that botulinum toxin A inhibits transmitter release from sensory nerve terminals
or urothelium, as well as efferent nerve terminals
A team of researchers led by JosEa Lemos from the University of Massachusetts Medical School examined the mechanisms at play during secretion of vasopressin from nerve terminals
in the posterior pituitary gland, which releases the neuropeptide into the blood so that it can make its way to the kidney and regulate water retention.
These cells, called solitary chemosensory cells, detect potential irritants and pass along the alert to pain-sensing nerve terminals
The toxin binds to cholinergic nerve terminals
and proteolytically inactivates SNAP-25, a synaptosomal-associated protein utilized in synaptic vesicle fusion with the nerve terminal