nerve sheath myxoma

nerve sheath myxoma

A benign, slow-growing peripheral nerve tumour averaging 1.5 cm in greatest dimension, which affects young adults (median age 35) and which arises in the dermis and/or subcutis of the extremities, especially of the hands and fingers, soft tissues, and within the spine. Recurrence is common when managed by simple excision. Prudence requires wide margins of grossly uninvolved tissue.

DiffDx
Myxoma, neurofibroma, perineurioma, schwannoma.
References in periodicals archive ?
Moreover, the neoplasm exhibited an abundant mucinous background, resembling nerve sheath myxoma, a benign entity described in people, but with no animal counterpart.
Various other terms also had been used for the dermal neoplasms, such as neurothekeoma, nerve sheath myxoma, benign myxoid tumor of nerve sheath, perineural myxoma, bizarre cutaneous neurofibroma.
Conjunctival myxoma can resemble other mixed or pure myxoma tumors, such as amelanotic naevus, amelanotic melanoma, dermal nerve sheath myxoma, myxoid neurofibroma, lymphangioma, lymphoma, reactive lymphoid hyperplasia, dermoid, myxoid liposarcoma, spindle cell lipoma, botryoid-type rhabdomyosarcoma, myxoid fibrous histiocytoma, and nodular fasciitis.
Other pathological differential diagnoses of our case would include hybrid peripheral nerve sheath tumors, perineurioma, cellular neurothekeoma, nerve sheath myxoma (classic neurothekeoma), desmoplastic neurothekeoma, superficial angiomyxoma (cutaneous myxoma), (16) solitary neurofibroma with prominent differentiation of Meissner bodies, or spindle cell carcinoma.
The histologic differential diagnosis in this case included a nerve sheath myxoma and a neurofibroma with myxomatous change, in addition to the myxoid angiomyoma.