nerve growth factor
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nerve growth fac·tor (NGF),
a protein (MW about 27,000) that controls the development of sympathetic postganglionic neurons and possibly also sensory (dorsal root) ganglion cells in mammals; similar factors have been isolated from the venom of several species of snakes; it has been isolated from the submaxillary glands of male mice, and when it is injected into newborn animals, sympathetic ganglia become hyperplastic and hypertrophic; stimulates synthesis of nucleic acids and protein.
Farlex Partner Medical Dictionary © Farlex 2012
nerve growth factor
n. Abbr. NGF
A protein that stimulates the growth of sympathetic and sensory nerve cells.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.
nerve growth fac·tor(NGF) (nĕrv grōth fak'tŏr)
A protein secreted by the neuron's target, critical for the survival and maintenance of sympathetic and sensory neurons. The movement of NGF from axon tip to soma is thought to be involved in the long-distance signaling of neurons; binds at least two receptors, which are capable of responding to this growth factor, TrkA (pronounced "Track A") and the LNGFR (for "low affinity nerve growth factor receptor") on the surface of cells.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
nerve growth factorA peptide substance that stimulates growth and differentiation of NEURONES in the sympathetic and sensory nervous system. Nerve growth factor has been found effective in promoting the healing of corneal ulcers due to loss of the sensory innervation of the cornea. Corneal transparency has been restored by this means.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005
nerve growth factor (NGF)a protein required for the maintenance of some types of neurone such as sympathetic and sensory neurones. It is produced by some nerve cell target tissues, e.g. smooth muscle. NGF also stimulates the production of nerve cell processes from developing neurones.
Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005
Nerve growth factor
A protein resembling insulin that affects growth and maintenance of nerve cells
Mentioned in: Numbness and Tingling
Gale Encyclopedia of Medicine. Copyright 2008 The Gale Group, Inc. All rights reserved.