DISCUSSION: A study of 5, 789 patients found myelinated nerve fibres
Following the onset of arthritis in the rats, however, these fibres began to sprout into the inflamed skin over the joint and wrap around the pain-sensing nerve fibres
They showed that the nerve fibres
could be guided to their correct targets using a particular growth factor - a biological chemical that promotes growth.
Generally there are still some nerve fibres
that are undamaged.
Instead the study found that long nerve fibre
connections were just as vital as short ones.
The damage disrupts messages travelling along nerve fibres
, either slowing them down, distorting them, preventing them from getting through and short circuiting them.
The team, led by Dr Georgio Terenghi at the Royal Free Hospital in London, has just started growing nerve fibres
through the polymer tubes in the laboratory.
Visual acuity is usually not affected in these cases; however Patient may have relative scotomas if sufficient number of myelinated nerve fibres
Unfortunately, as people with MS age, remyelination decreases significantly, resulting in more nerve fibres
being permanently lost.
The breakthrough came after tests on adult rats, conducted by a team of scientists based at the National Institute for Medical Research, confirmed that severed nerve fibres
located in the spinal cord could be reunited with the brain.
Tests on adult rats, by a team of scientists based at the National Institute for Medical Research, confirmed severed nerve fibres
could be re-engaged with the brain.
The source of the increased CGRP was thought to be certain types of sensory nerve fibres
in the skin that normally make and release a type or "isoform" called CGRP-alpha.