nephrocalcinosis


Also found in: Dictionary, Thesaurus, Encyclopedia, Wikipedia.
Related to nephrocalcinosis: medullary sponge kidney

nephrocalcinosis

 [nef″ro-kal″sĭ-no´sis]
deposition of calcium phosphate in the renal tubules, resulting in renal insufficiency.

neph·ro·cal·ci·no·sis

(nef'rō-kal'si-nō'sis),
A form of renal lithiasis characterized by diffusely scattered foci of calcification in the renal parenchyma; deposits of calcium phosphate, calcium oxalate monohydrate, and similar compounds are usually demonstrable radiologically.
[nephro- + calcinosis]

nephrocalcinosis

Nephrology A condition, more common in premature infants, especially if receiving loop diuretics, characterized by calcium oxalate or calcium phosphate deposits in renal tubules and interstitium, resulting in ↓ renal function Etiology Hypercalcemia,↑ Ca2+ excretion, medullary sponge kidney, renal cortical necrosis, renal tubular acidosis, TB Clinical Obstructive uropathy, possibly renal failure. See Kidney stones.

neph·ro·cal·ci·no·sis

(nef'rō-kal-si-nō'sis)
A form of renal lithiasis characterized by diffusely scattered foci of calcification in the renal parenchyma; deposits of calcium phosphate, calcium oxalate monohydrate, and similar compounds are usually demonstrable radiologically.

nephrocalcinosis

The presence of calcification or actual stones within the substance of the kidney.

neph·ro·cal·ci·no·sis

(nef'rō-kal-si-nō'sis)
Renal lithiasis characterized by diffusely scattered foci of calcification in the renal parenchyma.
References in periodicals archive ?
Nephrocalcinosis in chronic glomerulonephritis: report of the youngest patient.
[7] reported a series of eight patients with atypical genetically determined Bartter syndrome type 1, including absence of nephrocalcinosis, absence of hypokalemia, and/or metabolic alkalosis in the first year of life as well as persistent metabolic acidosis mimicking distal renal tubular acidosis.
The patient's history of pancreatitis in 2015 and nephrolithiasis in 2009 and evidence of both maternal and fetal nephrocalcinosis on imaging support longstanding hypercalcemia.
Insulin receptor and the kidney: nephrocalcinosis in patients with recessive INSR mutations.
(5) At-risk infants should be evaluated for nephrocalcinosis with abdominal ultrasonagraphy.
Diagnosis of PH should be suspected in any child with a first kidney stone, in adults with recurrent stone disease, any subject with nephrocalcinosis especially when associated with decreased GFR, and any subject with oxalate crystals in any biological fluid or tissue (Cochat et al., 2012).
Caption: Figure 2: Abdominal CT scan showing solitary left kidney with kidney cyst and nephrocalcinosis.
The increased calcium level may cause salt to be deposited in the soft tissues, with the consequent involvement of sclera (band keratitis), tendons (calcific tendonitis), joint cartilage (chondrocalcinosis and arthralgia), kidney parenchyma (nephrocalcinosis), and the pancreas.
Distal RTA can also lead to increased loss of urinary calcium resulting in osteopenia, osteomalacia, nephrocalcinosis, and even secondary hyperparathyroidism [2].
Nephrocalcinosis Symptomatic and prednisolone Kawashima et Osteomalacia, Symptomatic and al.
Renal ultrasound on admission revealed bilateral nephrocalcinosis type IIa.
In one study, 8 of 11 necropsied satin guinea pigs showed interstitial nephritis, pyelonephritis, and nephrocalcinosis [2], Massop (2009) found bilaterally cystic kidneys in one satinguineapigsuffering from SGPS, and Stoffels-Adamowicz (2014) encountered glomerular basal membrane thickness and larger parathyroid glands in 7 necropsied satin guinea pigs, compared with 4 control animals.