All renal biopsies, which were presented with features of
nephritic syndrome received in Department are analysed (Since the number of sample size is less as compared with the previous year statistics).
Blood in urine, proteinuria less than 3 gm/day, proteinuria of nephrotic range,
nephritic syndrome and acute kidney injury are the common presentations of GN but it may present with chronic kidney disease in some situations1-3.
Clinical features in various subjects included hematuria, renal failure, nephrotic and
nephritic syndromes, systemic disease with evidence of renal involvement, edema and presence of urinary abnormalities.
The clinical presentation of lupus nephritis is highly variable, ranging from asymptomatic hematuria and/or proteinuria to frank
nephritic syndrome to rapidly progressive glomerulonephritis with loss of renal function.17 Lupus nephritis, which was mainly glomerulonephritis was present in 75.4% of our patients, out of which 24.6% had class IV lupus nephritis, and 18.0% had full-blown
nephritic syndrome at presentation.
The principal causes of chronic kidney disease (CKD) in children comprise the following: disruptive uropathy, or dysplastic kidneys, reflux nephropathy, focal segmental glomerulosclerosis as a alternative of childhood
nephritic syndrome polycystic kidney disease, autosomal-recessive and autosomal-dominant varieties.
In the 80's, the clinical spectrum of HIV-associated renal disease was described as nephrotic and
nephritic syndrome, acute kidney injury (AKI), chronic kidney disease (CKD), and non-nephrotic proteinuria (14).
NGAL was higher in
nephritic subjects (NGALp nephrotic, 39.2 (5.0-213.0) versus subnephrotic, 23.5 (2.3-70.4), p < 0.042).
(1) In Mexico, the flowers infusion is used as a treatment for enterocolitis, gastroenteritis, hepatic and
nephritic colics, but it is mostly generally used due to its depressant activity.
With respect to pathophysiology of paraproteinemia-associated C3GP and DDD, it has been suspected but not proved that the paraprotein is functioning as an autoantibody that stabilizes C3 convertase (C3
nephritic factor) or possibly inhibits one of the CRPs, such as Factor H or I [9,10].
The patient with LN is likely to present with
nephritic syndrome (oliguria, minimal proteinuria, haematuria, hypertension and azotaemia) or with features of nephrotic syndrome (anasarca, heavy proteinuria and hypoalbuminaemia).
He has battled kidney disorders since the end of 1995 when he was diagnosed with
nephritic syndrome and had a kidney transplant in 2004.
Lomu's record of 37 tries in 63 tests was an impressive haul, all the more so considering he played much of his career and with
nephritic syndrome, the disease that attacked his kidneys.
