neonatal thrombocytopenia

neonatal thrombocytopenia

A state that is the most common cause of purpura during the neonatal period, defined by platelets < 150,000/µL
Neonatal thrombocytopenia–causes
Platelet consumption
• Immune-mediated Autoimmune, alloimmune–ITP or SLE in mother, platelet antibodies from mother
• Nonimmune Thrombin generation, infections
platelet production Amegakaryocytic thrombocytopenia, aplastic anemia, myeloinfiltrative processes
Others Drugs, hypoxia, inherited metabolic disorders, hypersplenism, associated with giant hemangiomas–Kasabach-Merritt syndrome  
References in periodicals archive ?
Lupus can cause other adverse pregnancy outcomes, including transient neonatal rash, neonatal thrombocytopenia, maternal preeclampsia, and recurrent fetal loss and thrombosis associated with antiphospholipid antibodies.
A prospective study on the prevalence and risk factors for neonatal thrombocytopenia and platelet alloimmunization among 9332 unselected Brazilian newborns.
The management of a lloimmune neonatal thrombocytopenia.
TAR syndrome is a rare autosomal recessive disorder characterized by neonatal thrombocytopenia and hypoplasia of the radial bones of the forearms with absent, short, or malformed ulnae.

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