neonatal thrombocytopenia

neonatal thrombocytopenia

A state that is the most common cause of purpura during the neonatal period, defined by platelets < 150,000/µL
Neonatal thrombocytopenia–causes
Platelet consumption
• Immune-mediated Autoimmune, alloimmune–ITP or SLE in mother, platelet antibodies from mother
• Nonimmune Thrombin generation, infections
platelet production Amegakaryocytic thrombocytopenia, aplastic anemia, myeloinfiltrative processes
Others Drugs, hypoxia, inherited metabolic disorders, hypersplenism, associated with giant hemangiomas–Kasabach-Merritt syndrome  
References in periodicals archive ?
Most studies on neonatal thrombocytopenia from developing countries like Nigeria have only centered on neonates admitted in intensive care units (4,5).
The finding also could offer big benefits for premature babies, opening the door to new treatments for a serious condition called neonatal thrombocytopenia that affects up to 30 percent of babies in neonatal intensive care units.
There was single incidence of neonatal thrombocytopenia. Rest all neonates had normal platelet count at birth.
Lupus can cause other adverse pregnancy outcomes, including transient neonatal rash, neonatal thrombocytopenia, maternal preeclampsia, and recurrent fetal loss and thrombosis associated with antiphospholipid antibodies.
TAR syndrome is a rare autosomal recessive disorder characterized by neonatal thrombocytopenia and hypoplasia of the radial bones of the forearms with absent, short, or malformed ulnae.
In the past decade there have been a lot of research article pouring in regarding the etiology, clinical profile and management of this entity, Neonatal Thrombocytopenia in the NICU's.
The criteria to diagnose gestational thrombocytopenia (GT) are normal platelet count before pregnancy, occurrence in late gestation, no fetal or neonatal thrombocytopenia and complete recovery with normal count following delivery.
Severe neonatal thrombocytopenia <50,000/[mm.sup.3] can be associated with increased risk of hemorrhage (14).

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