neonatal hypoglycemia


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ne·o·na·tal hy·po·gly·ce·mi·a

[MIM*240900]
familial onset of symptomatic hypoglycemia during infancy, with persistently low blood glucose; a variant form [MIM*240800] is induced by leucine with hyperinsulinism and variable mental retardation.
References in periodicals archive ?
Neonatal hypoglycemia, with associated risks for neonatal ICU admission, seizures, and neurologic injury, is more common in women with GDM, said Dr.
There was no increase in chorioamnionitis nor neonatal sepsis in the betamethasone group.2 Although neonatal hypoglycemia increased (24% vs 15%; number needed to harm=11.1; RR=1.60; 95% CI, 1.37-1.87; Pc.001), no increase was seen in intermediate care nursery or ICU stays (41.8% vs 44.9%; RR=0.93; 95% CI, 0.85-1.01; P=.09) nor length of hospital stay (7 vs 8 days; P=.20).
It is difficult to define exact numerical value of pathologic neonatal hypoglycemia. Transient hypoglycemia normally occurs after birth and most neonates are asymptomatic, however, some are symptomatic at the same or even higher blood glucose levels.
Outcome at 2 years after dextrose gel treatment for neonatal hypoglycemia: Follow-up of a randomized trial.
It was estimated using the method of sample size estimation for comparing two means on www.openepi.com with mean and standard deviation of neonatal outcomes, hypoglycemia, and NICU admissions with an expected difference of 30% reduction in NICU stay and 5-10% reduction in neonatal hypoglycemia between metformin and insulin treated groups from a study done in South Asian country [11] with 5% margin of error and 95% confidence interval.
The relationship of neonatal hypoglycemia with the type of diabetes and neonatal [Ak.sub.1] phenotype was reported in table 3.
According to this observation, brain damage and cognitive deficit were associated with neonatal hypoglycemia: neonatal encephalopathy [67], lesion of the occipital lobe and cortex [68-70], and reduction of the circumference of the head [71].
Neonatal hypoglycemia adversely affects the neurodevelopmental outcome, overall IQ, reading ability, arithmetic proficiency, and motor performance [6].
Early onset phenotype VLCAD deficiency is a severe and life-threatening defect of long-chain fatty acid oxidation that is often characterized by neonatal hypoglycemia followed by hypertrophic cardiomyopathy and cardiac failure.
The primary outcomes of macrosomia (birth weight >90th centile), fetal hyperinsulinemia (cord C-peptide >90th centile), clinical neonatal hypoglycemia, and primary cesarean section were all related to each of the 3 plasma glucose measurements (fasting, 1 h, and 2 h) in a continuous fashion, down to the lowest concentrations of glucose, with no inflection points (Fig.
The definition of neonatal hypoglycemia has been extensively discussed in the literature (25,26).

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