neonatal hepatitis

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ne·o·na·tal hep·a·ti·tis

hepatitis in the neonatal period presumed to be due to any of a variety of causes, chiefly viral; characterized by direct and indirect bilirubinemia, hepatocellular degeneration, and appearance of multinucleated giant cells; may be difficult to distinguish from biliary atresia, but is more likely to end with recovery, although cirrhosis may develop.
Farlex Partner Medical Dictionary © Farlex 2012

neonatal 'hepatitis'

A generic term for diseases of the newborn hepatic parenchyma, commonly associated with ↑ conjugated hyperbilirubinemia Diagnosis Requires ≥ 3 of following: fatty changes, cholestasis, bile duct proliferation, fibrosis, pseudoacini, cirrhosis Etiology Infection–syphilis, listeriosis, HBV, rubella, CMV, echovirus, adenovirus, toxoplasmosis, metabolic disease–α1-antitrypsin deficiency, cystic fibrosis, Wilson's disease, galactosemia, fructosuria, tyrosinemia, mechanical–choledochal cysts, intrahepatic ductal atresia hypoplasia, familial intrahepatic cholestasis, HDN, etc. See Hemolytic disease of the newborn. Cf Giant cell hepatitis.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.

ne·o·na·tal hep·a·ti·tis

(nē'ō-nā'tăl hep'ă-tī'tis)
The disorder in the neonatal period attributable to a variety of causes, chiefly viral.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

ne·o·na·tal hep·a·ti·tis

(nē'ō-nā'tăl hep'ă-tī'tis)
Neonatal disorder due to chiefly viral pathogens.
Medical Dictionary for the Dental Professions © Farlex 2012
References in periodicals archive ?
Subsequently the patients were classified into three diagnostic subgroups on the basis of hepatobiliary scintigraphy including biliary atresia, normal and neonatal hepatitis. Microsoft Excel 2010 was used for data entry and Graph Pad Software tool was utilized for analysis of categoricand numeric variables15.
Clinical and laboratory features of neonatal hepatitis of different etiology.
AST was significantly higher in the neonatal hepatitis group than in the other two groups (p<0.05).
Yamashiro-Kanashiro, "Neonatal hepatitis and lymphocyte sensitization by placental transfer of propylthiouracil," Journal of Endocrinological Investigation, vol.
Causes of cholestatic jaundice in a cohort of 74 patients Cause N Biliary atresia 39 (27 evaluable) Non-biliary atresia 34 (31 evaluable) Neonatal hepatitis 10 Choledochal cyst 9 Viral enterocolitis 5 HIV hepatitis 3 Gallstones 1 Auto-immune 1 Miscellaneous 2
Neonatal hepatitis and congenital insensitivity to adrenocorticotropin (ACTH).
(79) It must be emphasized, however, that variable degrees of ductular reaction (albeit generally of milder degree than in biliary atresia) may also be seen in a variety of nonobstructive liver diseases, including neonatal hepatitis of various etiologies (77,80); therefore, this finding must be interpreted with caution (see "Differential Diagnosis and Diagnostic Pitfalls" below).
Neonatal hepatitis was diagnosed in a similar incidence as with Ahmed et al2, and Monajemzadeh et al.9 While the diagnosis of extra hepatic biliary atresia was lower in our series, 6.25%, in contrast to Ahmed et al 20%, and 11.8% in the Omani series14, our people do not accept suggestions easily for surgical interventions in young babies, this is why they probably do not accept referrals for such reasons.
"Signs of neonatal hepatitis B are usually not present at the time of birth but may be detected between 2 weeks and 5 months of age" (Borkowsky & Krugman, 1998, p.169).
In addition, among 832 infants identified by a neonatal hepatitis B surveillance and vaccination program in New York City in 1988, only 59% had received HBIG and completed the vaccine series by age 18 months (9 ).
Any young child who presents with yellow skin, poor growth and abnormal blood tests along with other clinical features has been said to have neonatal hepatitis. The use of this term, however, gives no indication as to the cause, the severity or the prognosis of the child's illness.
Transmission of hepatitis B virus (HBV) from an asymptomatic chronic carrier mother to her newborn infant has been shown to result in acute neonatal hepatitis and in long-term serious liver disease.

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