neomycin


Also found in: Dictionary, Thesaurus, Encyclopedia, Wikipedia.

neomycin

 [ne″o-mi´sin]
a broad-spectrum aminoglycosideantibiotic produced by Streptomyces fradiae, effective against a wide range of gram-negative bacilli and some gram-positive bacteria. It is used, as the sulfate salt, for urinary tract irrigation, administered orally to prepare the bowel for surgery, and applied to the skin, eyes, and ears to treat infections due to susceptible organisms. In topical preparations it is often combined with other antibiotics or antiinflammatory steroids.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

neomycin

(nē′ə-mī′sĭn)
n.
A broad-spectrum antibiotic produced from strains of the actinomycete Streptomyces fradiae and used especially in the form of its sulfate as an intestinal antiseptic in surgery.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

neomycin

Infectious disease A broad-spectrum aminoglycoside antibiotic obtained from Streptomyces fradiae, which is generally effective against gram-negative rods and some gram-positive cocci
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.

neomycin

An aminoglycoside antibiotic drug derived from a strain of Streptomyces fradiae . Neomycin can be given by mouth to destroy organisms in the bowel or can be used in solution to irrigate the bladder. It is poorly absorbed into the bloodstream. It is much too toxic to be given by injection and can have seriously damaging effects on hearing and on the kidneys. The drug is widely used as a surface application in ointments with other ingredients such as steroids. A brand name is Nivemycin. Preparations of neomycin with a corticosteroid, for external use, include Audicort, Betnovate-N, Dermovate-NN, Maxitrol, Neo-Cortef, Synalar-N, Tri-Adcortyl and Vistamethasone N. The drug is also formulated with the antibiotics polymyxin and gramicidin and with the antifungal drug nystatin.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005
References in periodicals archive ?
i) Penicillin, streptomycin, oxytetracycline and neomycin are the antibiotics most often used in planktonic cultures with success, individually or in combination and they must be prioritized in the choice, either for phytoplanktonic or zooplanktonic organisms.
At 7 dpf, larvae were divided into three groups: control (i.e., 0) and 0.16 [micro]M and 1.6 [micro]M neomycin treatment.
Conclusion: Topical Ciprofloxacin is a better drug for the treatment of CSOM as compared to topical Neomycin.
Overall, increasing the neomycin concentration in treatment conditions correlated with decreasing percentages of intact hair cells, increasing percentages of damaged hair cells, and increasing percentages of missing hair cells in the region of interest (Fig.
Screening the electroporated cells was done for antibiotic resistance and performed on nutrient agar plates supplemented with 5 and 10 mg/ml of neomycin '4.
coli isolates were found highly sensitive to Ciprofloxacin (71.58%), Gentamicin (66.32%), Neomycin (54.74%) and Co-trimoxazole (53.68%).
Kanamycin, geneticin (G-418), and neomycin were purchased from Sigma Chemical Company.
The present work was directed at optimization of medium components, which have been initiated to play very capital role in decorating the neomycin production, with the accommodate of Placket Burman design and central composite design.
For example, Timor and co-worker have synthesized a set of modified neomycin B analogues by adding additional sugar at the C5''-OH of ring III and prepared a series of pseudo-pentasaccharides 1a- d (Fig.
Neomycin sulphate tablets (500 mg each) were purchased from Memphis Co.
As with all aminoglycosides, neomycin is limited in its clinical applications due to its serious adverse effects (Adams & Holland, 2011).