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neoadjuvant chemotherapyChemotherapy given before cancer surgery with the hope that it will shrink the tumour, resulting in a procedure that is less drastic and has clearer margins.
Breast, colorectal, lung cancers.
Nausea, vomiting, hair loss, fatigue, oral ulcers, infection, anaemia, increased bleeding.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
neoadjuvant chemotherapyInduction chemotherapy, neoadjuvant therapy, preemptive chemotherapy, primary chemotherapy Oncology 1. The use of chemotherapy on solid–ie, non-hematopoietic neoplasms–eg, osteosarcomas, anal cancer, head&neck cancer; NC is used in Pts with clinically resectable but locally advanced disease that is not amenable to complete eradication surgery or RT; agents used in NC include cisplatin, 5-FU, vinblastine, and the M-VAC 'cocktail.' See Neoadjuvant therapy. Cf Induction therapy.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.
Treatment of the tumor with drugs before surgery to reduce the size of the tumor.
Mentioned in: Neuroblastoma
Gale Encyclopedia of Medicine. Copyright 2008 The Gale Group, Inc. All rights reserved.