neglected disease


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neglected disease

A popular term for any of the major tropical infections other than “the big three”—HIV/AIDS, malaria, tuberculosis—which are endemic in developing regions of Central and South America, Asia and Africa, and, despite the large number of people infected, have much lower levels of international funding for prevention and treatment than the big three.

Neglected diseases, in decreasing frequency
Roundworm (ascariasis), whipworm (trichuriasis), hookworm (necatoriasis, ancylostomiasis), schistosomiasis, filariasis, trachoma, kala-azar/leishmaniasis, Chagas disease, leprosy, African trypanosomiasis, Guinea worm/dracunculiasis, Buruli ulcer.

neglected disease

Any disease affecting a large number of people, esp. in developing nations, who receive little attention from governments, medical researchers, and pharmaceutical companies. The term is used to raise social awareness of the illness among public health practitioners and citizens of Western nations. Examples of neglected diseases include Chagas disease, leishmaniasis, malaria, malnutrition, sleeping sickness, and tuberculosis.
See also: disease
References in periodicals archive ?
Such impacts occur where other neglected diseases break out but do not get reported.
The trend in approvals is clearly going in the right direction, but annual R&D spending to treat neglected diseases has leveled off at $3 billion in total, after rising rapidly from 2000 to 2007, which is a cause of concern," points out Joshua Cohen, assistant professor at Tufts CSDD who served as principal investigator on the study.
Developing new health technologies for neglected diseases is a difficult business strategy to pursue.
Don remains upbeat about the current challenges regarding neglected disease R&D.
They employ empirical data about neglected diseases and the current pharmaceutical market to draw support for a scheme encouraging vaccine development for such diseases.
Those stricken with neglected diseases do not constitute a valuable enough market to stimulate adequate R&D for new medicines by the multinational pharmaceutical industry.
According to the report, product development partnerships (PDPs) -- a unique public-private partnering mechanism created to increase biopharmaceutical participation in neglected disease R&D, government agencies, and academic institutions -- are driving this biotechnology company partnering for neglected diseases.
Partnering is an important driver for today's biotechnology companies, according to the report, "Biotechnology: Bringing Innovation to Neglected Disease Research and Development" The research finds 64% of all products in development by biotechnology companies across the pipeline of drugs, vaccines and diagnostics for neglected diseases involve partnering.
The new designation follows the release of a recent report concluding that high blood pressure is a neglected disease in the U.
The TRND program provides an opportunity to partner with and gain access to rare and neglected disease drug development capabilities, expertise, and clinical/regulatory resources in a collaborative environment with the goal of moving promising therapeutics into human clinical trials.
Global health experts, healthcare providers, people living with RHD and others called for new action against this easily preventable but neglected disease, which is a major cause of serious illness and death among women, children and adolescents in developing countries.
The articles published over these two special issues will provide valuable insights into the current contributions of medicinal chemistry efforts to neglected disease research, said Dr Kaneko.