neglected disease


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neglected disease

A popular term for any of the major tropical infections other than “the big three”—HIV/AIDS, malaria, tuberculosis—which are endemic in developing regions of Central and South America, Asia and Africa, and, despite the large number of people infected, have much lower levels of international funding for prevention and treatment than the big three.

Neglected diseases, in decreasing frequency
Roundworm (ascariasis), whipworm (trichuriasis), hookworm (necatoriasis, ancylostomiasis), schistosomiasis, filariasis, trachoma, kala-azar/leishmaniasis, Chagas disease, leprosy, African trypanosomiasis, Guinea worm/dracunculiasis, Buruli ulcer.

neglected disease

Any disease affecting a large number of people, esp. in developing nations, who receive little attention from governments, medical researchers, and pharmaceutical companies. The term is used to raise social awareness of the illness among public health practitioners and citizens of Western nations. Examples of neglected diseases include Chagas disease, leishmaniasis, malaria, malnutrition, sleeping sickness, and tuberculosis.
See also: disease
References in periodicals archive ?
Developing new health technologies for neglected diseases is a difficult business strategy to pursue.
Rob Don, director of Drug Discovery and Preclinical Research at the Drugs for Neglected Diseases Initiative (DNDi), outlined how this situation developed: "There was a lack of commercial viability, either as a push (e.g.
From 2000 to 2008, an average of 2.6 new drug products--including new molecular entities, vaccines, indications, combinations and formulations --were approved each year to combat neglected diseases. That number increased to an average of five per year in the 2009-2012 period, according to Tufts CSDD.
Those stricken with neglected diseases do not constitute a valuable enough market to stimulate adequate R&D for new medicines by the multinational pharmaceutical industry.
Partnering is an important driver for today's biotechnology companies, according to the report, "Biotechnology: Bringing Innovation to Neglected Disease Research and Development" The research finds 64% of all products in development by biotechnology companies across the pipeline of drugs, vaccines and diagnostics for neglected diseases involve partnering.
Rabies is considered as a neglected disease that largely affects vulnerable populations including the rural poor who do not have adequate access to information and health services.
The new designation follows the release of a recent report concluding that high blood pressure is a neglected disease in the U.S.
In conjunction, Anacor will establish an expanded library of boron compounds to screen for additional potential drug candidates to treat neglected diseases and will provide access to the expanded library compounds for neglected disease research to the Gates Foundation and others, including academic, governmental and other non-profit institutions or equivalent entities.
Commenting on this program, Prakash S Kayal, Senior Director and Business Head, Virology Division, Biocon said: "Hepatitis C (HCV) is a neglected disease, with very little public awareness on disease and its implications, if left untreated.
Global health experts, healthcare providers, people living with RHD and others called for new action against this easily preventable but neglected disease, which is a major cause of serious illness and death among women, children and adolescents in developing countries.
The list of essential diagnostics also focuses on additional infectious diseases prevalent in low- and middle-income countries such as cholera, and neglected diseases like leishmaniasis, schistosomiasis, dengue, and zika.
'Our partner in this campaign, Drugs for Neglected Diseases initiative (DNDi) and the Foundation for Innovative New Diagnostics (FIND) will ensure that all Malaysians have the opportunity to be tested and treated for this disease for free.