neglected disease


Also found in: Dictionary, Thesaurus, Legal, Encyclopedia.

neglected disease

A popular term for any of the major tropical infections other than “the big three”—HIV/AIDS, malaria, tuberculosis—which are endemic in developing regions of Central and South America, Asia and Africa, and, despite the large number of people infected, have much lower levels of international funding for prevention and treatment than the big three.

Neglected diseases, in decreasing frequency
Roundworm (ascariasis), whipworm (trichuriasis), hookworm (necatoriasis, ancylostomiasis), schistosomiasis, filariasis, trachoma, kala-azar/leishmaniasis, Chagas disease, leprosy, African trypanosomiasis, Guinea worm/dracunculiasis, Buruli ulcer.

neglected disease

Any disease affecting a large number of people, esp. in developing nations, who receive little attention from governments, medical researchers, and pharmaceutical companies. The term is used to raise social awareness of the illness among public health practitioners and citizens of Western nations. Examples of neglected diseases include Chagas disease, leishmaniasis, malaria, malnutrition, sleeping sickness, and tuberculosis.
See also: disease
References in periodicals archive ?
Elimination of neglected diseases and other poverty-related infections.
Scientists are aware of molecules that could potentially treat neglected diseases, but they have been mostly unable to make a business case for spending millions of dollars testing those molecules," Ridley explains.
Collins said he was particularly excited about five instances in which the NIH is using this new model of helping to "de-risk" the drug development process for orphan or neglected diseases through TRND.
They employ empirical data about neglected diseases and the current pharmaceutical market to draw support for a scheme encouraging vaccine development for such diseases.
Those stricken with neglected diseases do not constitute a valuable enough market to stimulate adequate R&D for new medicines by the multinational pharmaceutical industry.
According to the report, product development partnerships (PDPs) -- a unique public-private partnering mechanism created to increase biopharmaceutical participation in neglected disease R&D, government agencies, and academic institutions -- are driving this biotechnology company partnering for neglected diseases.
Through its Humanitarian Assistance for Neglected Diseases initiative, Genzyme is participating in efforts to discover and advance novel treatments for neglected diseases affecting the developing world.
Stinchcomb continued, "BVGH's efforts to improve access to funding and market information should encourage more biotechnology companies to join in the development of therapeutics, vaccines and diagnostics for these and other neglected diseases.
today announced that it has entered into a research collaboration with The National Institutes of Health (NIH) Therapeutics for Rare and Neglected Diseases (TRND) program.
The articles published over these two special issues will provide valuable insights into the current contributions of medicinal chemistry efforts to neglected disease research, said Dr Kaneko.
A European SME would have most of the benefits of this project: it would allow to further develop a vaccine against this neglected disease and increase the possibility to out-license this vaccine for commercialization.