nedocromil sodium


Also found in: Dictionary.
Related to nedocromil sodium: imipramine, cromolyn sodium, Tilade

mast cell stabilizers

Prophylactic drugs used to treat allergic conjunctivitis, vernal conjunctivitis, giant pupillary conjunctivitis, superior limbic keratoconjunctivitis. They act by stabilizing the membranes of mast cells thus preventing the release of histamine. Common agents are sodium cromoglicate (cromolyn sodium), lodoxamide, nedocromil sodium, olopatadine hydrochloride and pemirolast potassium. See antihistamine; hypersensitivity.
Millodot: Dictionary of Optometry and Visual Science, 7th edition. © 2009 Butterworth-Heinemann
References in periodicals archive ?
Nedocromil sodium has also been shown to be of potential use in reducing high-dose inhaled steroid use.
(23.) Jones P and the Nedocromil Sodium Quality of Life Study Group.
Cromolyn sodium and nedocromil sodium are non-steroidal treatments that may also be inhaled and used as "controller" medication rather than for treating symptoms once they've developed.
Is nedocromil sodium an effective prophylaxis for EIB in children?
They include nedocromil sodium, antihistamines and ketotifen.
(13-16) The logic of such a treatment might be questioned since sodium cromoglicate is not considered to have any constitutive anti-inflammatory activity; the removal of the stimulus to inflammation should help and better results might be obtained with other mast cell stabilisers/anti-eosinophil drugs such as lodoxamide or nedocromil sodium (both available to AS optometrists).
Nedocromil sodium exerts its anti-inflammatory and antiasthmatic effect by inhibiting the activation and activity of multiple inflammatory cells, including mast cells, eosinophils, airway epithelial cells and sensory neurons.
Nedocromil sodium for preventing exercise-induced bronchoconstriction.
The multicenter Childhood Asthma Management Program (CAMP) found no differences in final height among randomized groups of 311 children on budesonide, 312 on nedocromil sodium (Tilade), and 418 on matching placebos.
For chronic and recurrent allergic conjunctivitis, part of an appropriate management approach is the use of 'mast cell stabilisers', (21) with several drugs marketed in the UK (eg, sodium cromoglicate, lodoxamide and nedocromil sodium).
Nedocromil Sodium - Nedocromil is marketed as Tilade in an MDI formulation.