necrotizing ulcerative periodontitis

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necrotizing ulcerative periodontitis (NUP)

an inflammatory destructive disease of the gingiva which progresses to destruction of the periodontium. Compare necrotizing ulcerative gingivitis (NUG).

nec·ro·tiz·ing ul·cer·a·tive per·i·o·don·ti·tis

(nekrŏ-tīz-ing ŭlsĕr-ă-tiv perē-ō-don-tītis)
Severe and rapidly progressive disease with distinctive erythema of the free gingiva, attached gingiva, and the alveolar mucosa; extensive soft tissue necrosis that usually starts with the interdental papillae and marked loss of periodontal attachment.
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Necrotizing ulcerative periodontitis associated with severe congenital immunodeficiency in a prepubescent subject: clinical findings and response to intravenous immunoglobulin treatment.