necrotizing sialometaplasia


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nec·ro·tiz·ing si·a·lo·met·a·pla·si·a

squamous cell metaplasia of the salivary gland ducts and lobules, with necrosis of the salivary gland lobules; seen most frequently in the hard palate.

necrotizing sialometaplasia

Oral pathology A benign self-limited reactive salivary gland inflammation, which may clinically and histologically mimic malignancy–eg, mucoepidermoid carcinoma; most occur in minor salivary glands–SG; it may occur in SGs of the upper aerodigestive tract, or larynx DiffDx Mucoepidermoid carcinoma, SCC

necrotizing sialometaplasia

(sī″ă-lō-met″ă-plā′zh(ē-)ă) [ sialo- + metaplasia]
An ulcerative oral lesion usually found on the palate, caused by inflammation of the salivary glands. It may simulate an oral malignancy.

nec·ro·tiz·ing si·a·lo·met·a·pla·si·a

(nekrō-tīz-ing sīă-lō-met-ă-plāzē-ă)
Squamous cell metaplasia of the salivary gland ducts and lobules; seen most frequently in the hard palate.
[G. sialon, saliva, + metaplasia]
References in periodicals archive ?
When it is involving the oral cavity, the most commonly involved sites are tongue, palate, buccal mucosa, gingiva, and pharynx and the differential diagnoses should include squamous cell carcinoma, hematologic malignancy, tuberculosis, other deep fungal infections, oral lesions of Crohn's disease, necrotizing sialometaplasia of the palate, and chronic traumatic ulcers.
Necrotizing sialometaplasia is a condition which mostly arises from palatal minor salivary glands.
We report a rare case of necrotizing sialometaplasia of the right lateral nasopharynx with extension into the right parapharyngeal space in a 39-year-old man.
The differential diagnosis precluded minor salivary gland tumors, necrotizing sialometaplasia & ulcers secondary to systemic diseases like HIV, diabetes & blood dyscrasias.
Necrotizing sialometaplasia: a practical approach to the diagnosis.
Necrotizing sialometaplasia (NSM) is a benign, self-healing lesion of salivary glands, which represents less than 1% of biopsied oral lesions.
Anneroth and Hansen4 proposed 5 histologic stages in the development and evolution of necrotizing sialometaplasia: infarction, sequestration, ulceration, repair, and healing.
Necrotizing sialometaplasia is a benign, spontaneously healing inflammatory condition.
Necrotizing sialometaplasia is a benign inflammatory process that involves the minor salivary glands, primarily those of the hard palate.
MECs must be distinguished from necrotizing sialometaplasia, chronic sialadenitis, cystadenoma, cystadenocarcinoma, squamous cell carcinoma, epithelial-myoepithelial carcinoma, clear cell carcinoma (not otherwise specified), and metastatic tumors.
Necrotizing sialometaplasia is a benign, self-limited, reactive inflammatory process that involves salivary glands.
(1) In our patient, the differential diagnosis included (1) benign fibrous and neural tumors with secondary ulceration, (2) a specific infection, and (3) perhaps necrotizing sialometaplasia. Salivary gland tumors, while common in the palate, are not usually found in the midline, although one of the authors (S.O.K.) has seen several during his career.

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