necrotizing encephalitis

nec·ro·tiz·ing en·ceph·a·li·tis

any encephalitis in which extensive brain necrosis occurs, for example, acute necrotizing hemorrhagic encephalomyelitis.
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The patient presented here was one of the rare cases with diffuse necrotizing encephalitis with lesions disseminated over the periventricular white matter, basal ganglia, thalamus, brainstem and cerebellum without an immunodeficiency syndrome.
Animal studies indicate that active viral replication and necrotizing encephalitis with diffuse perivascular infiltrates of lymphocytes and maerophages occur in cerebral parenchyma (9,10).
Herpes simplex virus type 1 (HSV-1), in addition to causing recurrent cold sores and corneal infections, may cause a severe necrotizing encephalitis in children and adults.