necrotising enterocolitis


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Related to necrotising enterocolitis: Necrotising fasciitis

necrotising enterocolitis

A disease of premature infants (incidence is inversely proportional to gestational age) affecting the terminal ileum 3–10 days after birth, which comprises about 2% of neonatal ICU admissions and 10% of admissions of premature infants or low-birth-weight neonates. Necrotising enterocolitis affects 10% of infants weighing < 1500g; up to 60% need surgery.

Clinical findings
Banal to fulminant disease with abdominal distension, vomiting, rectal bleeding, intestinal gangrene, perforation, sepsis and shock.

Imaging
Pneumatosis intestinalis.

Prevention
NEC is rare in breast-fed children, who may be protected by IgA in maternal milk; oral IgA-IgG solution in LBW infants may be protective.

Mortality
20–25%
References in periodicals archive ?
Vasarhelyi, "Genetic variants of the interleukin-18 promoter region (-607) influence the course of necrotising enterocolitis in very low birth weight neonates," European Journal of Pediatrics, vol.
Timely intervention with parenteral amphotericin B in surgically treated cases suspected to have necrotising enterocolitis might reduce the hidden mortality due to fungal sepsis and all infants with bowel surgery done for perforating or inflammatory lesions should be subjected to careful histopathological examination, else atypical causes for bowel perforations like GIM might be missed.(4)
(6) Causes of neonatal gastro-intestinal perforation include necrotising enterocolitis, bowel obstruction (i.e.
A reduction of necrotising enterocolitis at Groote Schuur Hospital nursery.
Doctors feared the infant wouldn't survive when he was struck down by necrotising enterocolitis (NEC), which caused his intestine to become inflamed and start to die.
Lead author Associate Professor Sanjay Patole, from UWA's School of Women's and Infants' Health based at King Edward Memorial Hospital, said death, and necrotising enterocolitis (NEC), a serious inflammatory bowel disease, were major issues in extremely premature babies worldwide.
Necrotising enterocolitis in the very low birthweight infant: expressed breast milk feeding compared with parenteral feeding.
Probiotics feeding in prevention of urinary tract infection, bacterial sepsis and necrotising enterocolitis in preterm infants: a prospective double-blind study.
She was born with necrotising enterocolitis, which meant the bowel dies and sufferers have to be fed intravenously, causing liver damage.
It points out that the majority of cases reported of infection with this bacterium have described neonates with sepsis, meningitis or necrotising enterocolitis as a consequence of the infection; the case fatality rate has been as high as 33%
Taylor conquered chronic lung problems - after spending her first eight months in hospital - and Kieran has beaten severe bowel condition necrotising enterocolitis.