necrogenic


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Related to necrogenic: necrogenic wart

necrogenic

 [nek″ro-jen´ik]
productive of necrosis or death.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

nec·ro·gen·ic

(nek'rō-jen'ik),
Relating to, living in, or having origin in dead matter.
Synonym(s): necrogenous
[necro- + G. genesis, origin]
Farlex Partner Medical Dictionary © Farlex 2012

nec·ro·gen·ic

(nek'rō-jen'ik)
Relating to, living in, or having origin in dead matter.
[necro- + G. genesis, origin]
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
References in periodicals archive ?
The extensive research focus on Wy-14,643 is particularly problematic, because a) it is typically administered at necrogenic doses well above those required for maximal responses; b) it is one of the few agonists that produce sustained, as opposed to only transient, enhancement of DNA synthesis in hepatocytes; c) unlike many other agonists, it preferentially activates rodent forms of PPAR-[alpha] (with humans exhibiting -20-fold less sensitivity); and d) humans apparently have never been exposed to it, either in an experimental or clinical setting.
They also demonstrated that necrogenic syndrome, a syndrome prevented by dietary selenium, was not prevented by addition of TMSe.
Inactivity of dietary trimethylselenonium chloride against the necrogenic syndrome of the rat.
In many animal models of multistage hepatocarcinogenesis, various tumor promoters are usually administered to the animals 2 weeks after the initiation with the necrogenic dose of DEN, at a time when the liver is recovered morphologically to the normal from the necrosis (5-7).
Besides inducing liver necrosis, a single necrogenic dose of DEN to rats can also cause a decrease in the level of hepatic growth hormone (GH) receptor (10), the expression of which is partly regulated by GH (11).
The present study clearly shows that DEN treatment at a necrogenic dose can cause acute toxicity to various cell types in the adenohypophysis and alter serum levels of several hormones.