USA], August 26 ( ANI ): Recent research shows that elevated levels of natriuretic peptides
in adipose tissue protect against effects of high-fat diet.
KEY WORDS: Recombinant human brain natriuretic peptide
, Acute myocardial infarction, Cardiac failure.
The receptors, termed natriuretic peptide
receptors (NPRs) are classified as types A and B.
State of the art: using natriuretic peptide
levels in clinical practice.
levels were similar in patients with normal diastolic function (n=16; NT-proBNP: median, 168 pmol/L; interquartile range, 118 to 289 pmol/L), an impaired relaxation pattern (n=24; NT-proBNP: median, 269 pmol/L; interquartile range, 164 to 778 pmol/L) or a pseudonormal pattern (n=5; NT-proBNP: median, 846 pmol/L; interquartile range, 398 to 2867 pmol/L).
Blood N-terminal pro-brain natriuretic peptide
levels were higher in cases than the controls (pless than 0.
The company added that the US Patent 8,580,747, entitled 'Cyclic Natriuretic Peptide
Constructs,' has composition of matter claims relating to its PL-3994 natriuretic peptide
receptor-A agonist for treatment of cardiovascular and pulmonary indications.
Rapid measurement of B-type natriuretic peptide
in the emergency diagnosis of heart failure.
It was observed that the level of brain natriuretic peptide
was not related to body weight (Graphic 1; p = 0.
Nile is initially focusing its efforts on developing its lead compound, cenderitide, a novel, rationally designed chimeric peptide for the treatment of heart failure, and CU-NP, a second novel, rationally designed natriuretic peptide
Plasma levels of B-type natriuretic peptide
(BNP) "had predictive utility for death, heart failure, and MI, even when adjusted for risk factors and structural abnormalities" of the heart in the general population, Dr.
BNP is a more robust prognostic marker than atrial natriuretic peptide
in the general population without heart failure," Dr.