Our study is the second study in the literature that measures hydroxyproline levels in a thin and nonhomogeneous tissue like
nasal mucosa. Consistent with the study of Bayraktar et al.
which are the symptomatic hallmarks found in an AR patient.15 The inflammatory responses include release of lymphocytes, eosinophils, neutrophils, and mast cell with elevated mucus secretion into
nasal mucosa.
aureus, a pathogen commonly hosted in the inflamed
nasal mucosa, and lower goblet cell counts are seen following intranasal administration of S.
Shrinkage was less in
nasal mucosa that was attached to cartilage than in free mucosa because the attachments to cartilage helped maintain mucosal dimensions.
In this case, the infection caused lesions throughout the facial skin,
nasal mucosa, and paranasal sinus, probably because the delay in accurate diagnosis allowed for wide dissemination of the pathogen.
After nasal surgery,
nasal mucosa is under process of healing and there is excessive crusting and nasal discharge which hurdle the proper delivery of topically applied steroids.
NP is a rare sinonasal tumor of unknown etiology, arising from
nasal mucosa, and representing 0.5-4% of all sinonasal tumors.
Sections prepared from the traumatized regions of the
nasal mucosa were stained with Masson's trichrome dye (which reveals wound healing better than does hematoxylin-and-eosin staining).
According to the Japanese guidelines for AR, the objectives of surgical treatment for AR include modulation of the
nasal mucosa, correction of the nasal cavity to improve nasal ventilation, and improvement of hyperreactivity with rhinorrhea [8].
Previous animal studies have supported this and described cases of severe nasal symptoms and
nasal mucosa remodeling that were observed in the mouse model with HDM-induced AR, but not noted in that with pollen-induced AR [16,17].
This method allows to assess the pathophysiological changes occurring in the
nasal mucosa and monitor response to applied treatment and thus has both diagnostic and therapeutic values.
We concluded that xylene might affect the cellular junctions in the
nasal mucosa. Cell-cell junctions are important to maintain cell and tissue polarity.
