narrow-spectrum antibiotic


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narrow-spectrum antibiotic

An antibiotic that is specifically effective against a limited group of microorganisms.
See also: antibiotic
References in periodicals archive ?
* MEPS-HC respondents may report one or multiple conditions that each drug fill was intended to treat and respondents may report using both a broad- and a narrow-spectrum antibiotic to treat the same condition.
There is no widely accepted definition of broad- versus narrow-spectrum antibiotics among PCPs or their professional organizations.
Both have clear advantages over narrow-spectrum antibiotics.
The intervention practices prescribed a much greater proportion of antibiotics belonging to narrow-spectrum antibiotic groups (penicillin, amoxicillin, erythromycin), and a lower proportion of antibiotics belonging to more expensive, second-generation macrolides (azithromycin, clarithromycin) compared with control practices (Table 2B).
A large number of studies have identified the factors limiting the practice of antibiotic de-escalation: the presence of MDR bacteria,[23] culture-negative results,[20] and initial narrow-spectrum antibiotics.[21] Herein, the de-escalation strategy was less common in trauma patients with high APACHE II scores, high ISS score, sepsis, MDR bacterial infection, inappropriate empirical antibiotic treatment, and late-onset VAP.
Higher knowledge scores were associated with using narrow-spectrum antibiotics, understanding the potential harm antibiotics can cause, trying alternative strategies such as explaining to patients the disease features that should prompt follow-up, and explaining duration of symptoms.
Guidelines often call for using narrow-spectrum antibiotics for shorter periods, in an effort to limit the development of antibiotic resistance.
Reviewing the need for early and Early identification of bacteria appropriate investigation, eg and antibiotic susceptibility blood cultures, for patients promotes shift from broad to suspected to have serious narrow-spectrum antibiotics. bacterial infection.
The economic realities of drug development mean that narrow-spectrum antibiotics aren't cost-effective for pharmaceutical companies to produce.
(2014) considered narrow-spectrum antibiotics to be penicillin, cloxacillin, cephalexin, cefadroxil, and erythromycin, and all other antibiotics were considered broad-spectrum.
The likelihood of adverse effects of broad-spectrum antibiotics, whose use is commonly indicated at the start of treatment, is greater than those of directed, narrow-spectrum antibiotics that can be used once sensitivities are known.
62% of children had at least one exposure to narrow-spectrum antibiotics and 41% to broad-spectrum antibiotics.
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