naringin


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naringin

(nar'i-jin),
A bioflavonoid responsible for the bitter taste in grapefruit.
[Sansk. naringa, orange tree, + -in]
Farlex Partner Medical Dictionary © Farlex 2012

naringin

A flavanone glycoside and major flavonoid in grapefruit, which gives grapefruit juice its tangy/bitter taste. Naringin is metabolised in vivo to the flavanone naringenin.
 
Health benefits
Antioxidant activity; lowers serum lipid levels.

Alleged health benefits
Reduced risk of cancer; reduced neurologic residua following stroke.

Pharmacologic effects
Naringin inhibits certain cytochrome P450 enzymes (e.g., CYP3A4 and CYP1A2); it also inhibits vascular endothelial growth factor (VEGF) release, which induces angiogenesis.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
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References in periodicals archive ?
Standards for HESP (hesperitin-7-O-rutinoside or hesperidin), NARG (naringenin), NAR (naringenin-7-O-neohesperidoside or naringin), and PON (isosakuranetin-7-O-neohesperidoside or poncirin) were obtained from Sigma (St.
Preventive effects of hesperidin, glucosyl hesperidin and naringin on hypertension and cerebral thrombosis in stroke-prone spontaneously hypertensive rats.
The Naringin imprinted P(AA-co-AN) membrane was 500 m thick [20] and the thickness of the dense top layer and membrane thickness of UA imprinted membrane were 10-20 m and 200-300 m [22] respectively while the pore diameter was found to be 0.1.
Materials and instruments: Quercetin isoquercitrin rutin hesperetin hesperidin naringenin naringin and icariin were generous gifts from Prof.
Gallic acid, pyrogallol, homogentisic acid, protocatechuic acid, (+) catechin, chlorogenic acid, caffeic acid, vanillin, ferulic acid, naringin, resveratrol, naringenin, hesperetin, formononetin and biochanin-A were used as standard for the detection of phenolic compounds from the fruiting bodies of P.
A number of natural molecules such as non-polar coumarins (imperatorin and isoimperatorin), myricitrin, gossypin, quercetin, naringin, kaempferol, apigenin, hypericin, cardiospermin, chrysin, cinnamic acid, pcoumaric acid, caffeic acid, ferulic acid, sinapic acid, sanjoinine A, obovatol, magnolol, honokiol and linalool, isolated from plants have shown promising anxiolytic activity (Fernandez et al.
led to the isolation of eighteen compounds, namely; octadecane (1), triacontyl palmitate (2), heptatriacontyl benzoate (3), 1-hentriacontanol (4), 1- heptatriacontanol (5), 14,20-dimethyl-1-heptacosanol (6), icosyl-p-hydroxy benzoate (7), b-sitosterol (8), stigmasterol (9), b-amyrin (10), mupinensisone (11), alpinetin (12), and pinostrobin (13), 3- oxoleane-9(11),12-diene-30-oic acid (14), 4',5,6-trihydroxy-7-methoxy-flavone (15), 2',4',5,7- tetrahydroxyisoflavone (16), b-sitosterol glucoside (17) and naringin (18).
Antioxidant Products: carotenoids (lutein and lyeopene), acerola extract, CoQ10, de-flavored sea buckthorn extract, acai extract, de-flavored teas (green tea catechins and black tea theaflavins), Indian gooseberry, apple polyphenols, natural vitamin E, citrus bioflavonoids (naringin and hesperidin)
Renuka, "Naringin regulates glutamate-nitric oxide cGMP pathway in ammonium chloride induced neurotoxicity," Biomedicine & Pharmacotherapy, vol.
Deligeorgis, "The influence of naringin or hesperidin dietary supplementation on broiler meat quality and oxidative stability," PLoS ONE, vol.
Li, "Naringin inhibits high glucose-induced cardiomyocyte apoptosis by attenuating mitochondrial dysfunction and modulating the activation of the p38 signaling pathway," International Journal of Molecular Medicine, vol.
Antioxidant Products: Carotenoids (lutein and lycopene); aronia juice extract; CoQ10; deflavored sea buckthorn extract; acai extract; de-flavored teas (green tea catechins and black tea theaflavins); resveratrol; apple polyphenols; natural vitamin E; citrus bioflavonoids (naringin and hesperidin)