naloxone hydrochloride


Also found in: Dictionary, Thesaurus.
Related to naloxone hydrochloride: Suboxone, naltrexone

nal·ox·one hy·dro·chlor·ide

(nal-ok'sōn hī'drō-klōr'īd),
A synthetic congener of oxymorphone, a potent antagonist of both endorphins and narcotics. Used to treat opiate overdose to reverse coma and respiratory depression; included in formulations of pentazocine to reduce the risk of abuse.

naloxone hydrochloride

[nal′əksōn]
an opioid antagonist.
indications It is prescribed for reversal of respiratory depression and other opioid effects in patients receiving opioid analgesics and in patients who have abused heroin, morphine, or other synthetic opioids.
contraindication Known hypersensitivity to this drug prohibits its use.
adverse effects Among the most serious adverse effects when given to opioid-dependent patients are side effects associated with opioid withdrawal.

nal·ox·one hy·dro·chlor·ide

(nal-ok'sōn hī'drŏ-klōr'īd)
A synthetic congener of oxymorphone, a potent antagonist of both endorphins and narcotics. Used to treat opiate overdose to reverse coma and respiratory depression.

nal·ox·one hy·dro·chlor·ide

(nal-ok'sōn hī'drŏ-klōr'īd)
Synthetic congener of oxymorphone, a potent antagonist of both endorphins and narcotics. Used to treat opiate overdose and to reverse coma and respiratory depression.
References in periodicals archive ?
Saved by the nose: Bystander-administered intranasal naloxone hydrochloride for opioid overdose.
This technology transfer is expected to allow the JV to produce naloxone hydrochloride API (active pharmaceutical ingredient) with quality meeting both European and Chinese pharmacopoeia specifications.
Naloxone hydrochloride API represents the first commercial opportunity for the JV, which is initially focusing on eight API products.
2006), who observed an increase in total length of seminiferous tubules and Sertoli cell population in rats treated with 8 [micro]g of naloxone hydrochloride per gram of body weight associated with a reduced tubular diameter.
Pharmacologically, naltrexone hydrochloride has more prolonged effect and greater ability to block opioid receptors compared to naloxone hydrochloride (BRUNTON, 2006).
Morphine hydrochloride, indomethecin, dexamethasone and naloxone hydrochloride were dissolved in physiological saline (0.
Aoxing Pharmaceutical (AMEX:AXN), a specialty pharmaceutical company, announced on Monday that the China Administrative Bureau of Industry and Commerce has granted a business license for the Naloxone Hydrochloride API product to Hebei Aoxing API Pharmaceutical Company Ltd, the joint venture between Aoxing Pharma and Macfarlan Smith Ltd.
Food and Drug Administration approved Targiniq ER (oxycodone hydrochloride and naloxone hydrochloride extended-release tablets), an extended-release/long-acting (ER/LA) opioid analgesic to treat pain severe enough to require daily, around-the-clock, long-term opioid treatment and for which alternative treatment options are inadequate.