naloxone


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naloxone

 [nal-oks´ōn]
an opioid antagonist structurally related to oxymorphone, used in the diagnosis and treatment of opioid toxicity, to reverse opioid-induced respiratory depression, and as an adjunct in the treatment of hypotension associated with septic shock; administered parenterally.

naloxone

(năl′ək-sōn′, nə-lŏk′sōn)
n.
A drug, C19H21NO4, used in its hydrochloride form as an antagonist to opioids such as morphine and in combination with buprenorphine for long-term treatment of opioid addiction.

naloxone

Narcan® An IV morphine and endorphin antagonist-type opioid analgesic. See Opioids, Reversal agent.

naloxone

A narcotic antagonist drug similar to NALORPHINE, chemically related to MORPHINE, and used as an antidote to narcotic poisoning. The drug is on the WHO official list. A brand name is Narcan.
References in periodicals archive ?
Clients were asked by POINT staff to give feedback about their experience using naloxone (Table 4).
And with the new arena came new marketing opportunities, apparently--the price of naloxone doubled about a year ago.
This service also includes a private consultation with the pharmacist or pharmacy technician to determine the patient's eligibility, training on naloxone administration and expectations and, when appropriate, notification to the patient's primary care provider.
"One could only hope that this extraordinary increase in prescribing of naloxone is contributing to that stabilization or even decline of the crisis," Katherine Keyes, a Columbia University drug abuse expert, said.
"Comprehensively addressing the opioid overdose epidemic will require efforts to improve naloxone access and distribution in tandem with efforts to prevent initiation of opioid misuse, improve opioid prescribing, implement harm reduction strategies, promote linkage to medications for opioid use disorder treatment, and enhance public health and public safety partnerships," the authors write.
There are currently three primary naloxone delivery systems (injection, auto-injection, and intranasal).
Lee's team has built a wearable device designed to detect when a person's respiration rate decreases to a certain level converted from electrocardiography (EKG) signals and then release naloxone, which blocks the opioid from binding to brain receptors.
Gold, MD, called improving access to naloxone the "single most important and impactful initiative to save lives and give people with opioid use disorders a second chance at treatment.
In 2015/16, our first full year of delivering naloxone in Birmingham, we distributed 179 naloxone kits.
- The US Food and Drug Administration has accepted for review the company's New Drug Application for its higher naloxone injection product candidate for the treatment of opioid overdose, US-based Adamis Pharmaceuticals Corp.
Following the forum, opioid overdose prevention training using Naloxone will be held at no charge for registered individuals.