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a quinolone antibacterial agent, active against most gram-negative bacteria causing urinary tract infection including Escherichia coli, Klebsiella and Enterobacter species, and some Proteus species. Pseudomonas species are generally resistant.
nal·i·dix·ic ac·id(nal-i-dik'sik as'id),
An orally effective antibacterial agent used in the treatment of genitourinary tract infections.
nalidixic acid/nal·i·dix·ic ac·id/ (nal-ĭ-dik´sik) a synthetic antibacterial agent used in the treatment of genitourinary infections caused by gram-negative organisms.
An antibacterial drug, C12H12N2O3, used to treat urinary tract infections caused by gram-negative bacteria.
indications It is prescribed in the treatment of certain urinary tract infections.
contraindications Renal or hepatic insufficiency, a history of convulsive disorders, or known hypersensitivity to this drug prohibits its use. It should not be used in children less than 3 months of age and should be used with care in prepubertal children.
adverse effects Quinolones have caused tendon rupture, especially in prepubertal children, and severe hypersensitivity reactions. Among the more serious effects are increased intracranial pressure, seizures, hemolytic anemia in people affected with glucose-6-phosphate dehydrogenase deficiency, and GI and neurological disturbances.
nalidixic acidAntibiotics An early generation quinolone with a limited antimicrobial palate, primarily used for UTIs. See Quinolone.
nalidixic acidA quinolone antibiotic drug, effective against GRAM NEGATIVE bacilli, including Proteus species, and much used for urinary infections. The drug is on the WHO official list. Brand names are Negram andUriben.
nal·i·dix·ic ac·id(nali-diksik asid)
Orally effective antibacterial agent used to treat genitourinary tract infections.
n an antibacterial prescribed in the treatment of urinary tract infections.
a naphthylidine derivative that inhibits DNA synthesis. Used for the treatment of urinary tract infections due to susceptible gram-negative bacteria. Side-effects in dogs include vomiting, diarrhea and seizures.