nNOS


Also found in: Acronyms.

nNOS

(en'nos),

NOS1

A gene on chromosome 12q14-qter that encodes neuronal nitric oxide synthase (nNOS), a widely expressed enzyme that produces nitric oxide (NO). A messenger molecule with diverse functions throughout the body, nNOS plays a role in a wide range of physiological and pathological processes, including neurotransmission, neurotoxicity, muscle contraction, sexual function, fluid homeostasis and atherosclerosis.
References in periodicals archive ?
Constructs-The cDNA corresponding to residues 14-131 of rat nNOS N-terminus was amplified and cloned into the yeast two-hybrid vectors pGAD and pGBT9 as well as in the recombinant expression vector pKLSLt.
La participacion de las RNS concuerda con el aumento en la actividad de la nNOS y la generacion de RNS, los cuales estan relacionados a la excitoxicidad por liberacion de glutamato (46).
Association between Parkinson's disease and polymorphisms in the nNOS and iNOS genes in a community-based case-control study.
nNOS and eNOS proteins are preferentially expressed in fast- and slow-twitch fibers, respectively(Lau et al.
After washing twice (5 minutes) in PBS, the sections were incubated for 12 to 14 hours with purified rabbit antibodies for AQP2-3 (Chemicon, Temecula, CA; 1:2000, 1:1000, 1:1000, respectively) and monoclonal rabbit antibodies against eNOS and nNOS (Santa Cruz, CA; 1:1000 and 1:1000, respectively) in PBS with 0.
Dystrophin not only helps build muscle cells, it's also a key factor to attracting nNOS to the muscles cells and helping nNOS bind to the cell and help repair it following activity," Yi Lai, lead author of the study, said.
Segundo, NOS1AP tambien tiene su blanco de nNOS a Dexras 1, que esta involucrada en la modulacion de la transduccion de senal, y de ese modo facilita su activacion dependiente de NO (19).
nNOS is involved in estrogen mediated neuroprotection in neuroblastoma cells.
Meanwhile, in the control group, while eNOS and nNOS immunoreactivities were detected in both epithelial and connective tissues, these immunoreactivities were more clear in the epithelial tissue (Figure 2B and 2C, Table 2).
HSP90 has been implicated in interactions with both eNOS and nNOS that have regulatory significance.
3-nitrotirozin duzeyleri KOAH'li hastalarin kaslarinda kontrol grubu ile karsilastirildiginda belirgin olarak yuksek ve nNOS protein duzeyleri ile iliskili izlenmis.