myxovirus


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myxovirus

 [mik´so-vi″rus]
any of numerous RNA viruses, some of which cause disease, now distinguished as either orthomyxoviruses or paramyxoviruses.

myx·o·vi·rus

(mik'sō-vī'rŭs),
Term formerly used for viruses with an affinity for mucins, now included in the families Orthomyxoviridae and Paramyxoviridae. The myxoviruses included influenza virus, parainfluenza virus, respiratory syncytial virus, measles virus, and mumps virus.

myxovirus

(mĭk′sə-vī′rəs)
n. pl. myxovi·ruses
A paramyxovirus or orthomyxovirus.

MX1

A gene on chromosome 21q22.3 that encodes a dynamin-like GTPase which acts as a cell-autonomous host restriction factor against many viral pathogens, including influenza viruses, rhabdovirus VSV, bunyavirus LACV, Thogoto virus, measles virus, Hanta virus, Coxsackie virus CVB, Rift Valley fever virus, HBV, and Crimean-Congo haemorrhagic fever virus.
References in periodicals archive ?
Further, we recently observed intense glomerular expression of human myxovirus resistance protein 1, a type-I-interferon- (IFN-) dependent transcript, in biopsy specimens from patients with lupus nephritis, whereas negative staining occurred in specimens from patients with IgA nephropathy or purpura nephritis.
Other genes reported to be associated with AA include the myxovirus resistance 1 (MX1) gene on chromosome 21q22.3 (Tazi-Ahnini et al., 2000) , autoimmune regulator (AIRE) gene on chromosome 21q22.3 (Buzi et al., 2003; Collins et al., 2006; Pforr et al., 2006), MHC class I polypeptide-related sequence A (MICA) gene on chromosome 6p21.3 (Barahmani et al., 2006), protein tyrosine phosphatase , non-receptor type 22 (PTNP22) gene on chromosome 1p13.3-p13.1 (Kemp et al., 2006), IL-1 receptor antagonists (IL1RN, IL1F5) genes on chromosome 2q14.2 (Tazi-Ahnini et al., 2002), macrophage migration inhibitory factor (MIF) gene on chromosome 22q11.23 (Shimizu et al., 2005),
Dentre os ISGs que aumentam sua expressao durante o inicio da gestacao em resposta ao IFNT, estao o 2',5' oligoadenilato sintetase (OAS; MIRANDO et al., 1991; SCHMITT et al., 1993; JOHNSON et al., 2001), o gene de resistencia ao myxovirus 1 (MX1; (OTT et al., 1998) e o gene estimulado pelo interferon 15 (ISG15; NAIVAR et al., 1995; AUSTIN et al., 1996; JOHNSON et al., 1999).
Purifying selection and positive selection on the myxovirus resistance gene in mammals and chickens.