Symptomatic delayed trans-dural herniation and strangulation of cauda equinae following resection of Myxopapillary ependymoma
. Br J Neurosurg.
The 2007 World Health Organization (WHO) classification of primary brain tumors distinguished four types of ependymal tumors based on their histological appearance: subependymoma (WHO grade I), myxopapillary ependymoma
(WHO grade I), ependymoma with cellular, papillary and clear cell variants (WHO grade II) and anaplastic ependymoma (WHO grade III) .
The benign tumors detected in the patients were tubular adenoma of the colon in one patient, pituitary adenoma in one patient, and intracranial myxopapillary ependymoma
in one patient.
(9) Individual tumor cells are often round to oval with scant or moderate eosinophillic cytoplasm and pleomorphic nuclei with rhabdoid and epitheloid cells scattered at periphery.9 ESMC expresses neuroendocrine differentiation with strong immunopositivity for vimentin and synaptophysin (7) and weak or focal positivity for EMA and S-100.7 Myxoid matrix with lobulated neoplastic cells is also seen in chordoma, parachordoma, chordoid meningiomas, and myxopapillary ependymoma
. However, chordomas stain positive for panCK and EMA and negative for GFAP while parachordomas are positive for EMA, S-100, panCK, and vimentin with abundant type IV collagen.
Surgical technique and outcomes in the treatment of spinal cord ependymomas: part II: myxopapillary ependymoma
Primary glial tumor of the retina with features of myxopapillary ependymoma
. Am J Surg Pathol.
The microscopic differential diagnosis includes chondrosarcoma, signet cell adenocarcinoma of the rectum, myxopapillary ependymoma
, and chordoid meningioma.
The following is a case of a young male patient presenting with low back pain and radicular symptoms caused by myxopapillary ependymoma
Tumors or cysts treated include a pineal cyst, lateral ventricle arachnoid cysts (n = 3), a large colloid cyst, a benign mixed astroglial cyst, low-grade gliomas (n = 4) (1 myxopapillary ependymoma
, 1 WHO grade II astrocytoma, 1 pilocytic astrocytoma, and 1 subependymal giant cell astrocytoma (SEGA)), a dysembryoplastic neuroepithelial-like tumor (DNET), an epidermoid tumor, an immature teratoma, a craniopharyngioma, a giant pituitary macroadenoma with intraventricular extension, and a pineal parenchymal tumor (intermediate differentiation).
The diagnosis was myxopapillary ependymoma
, a type of spinal tumor.
Microscopic differential diagnosis includes chondrosarcoma, signet ring adenocarcinoma of rectum, osteosarcoma, myxopapillary ependymoma
. The close differential diagnosis on cytology chondrosarcoma can be differentiated by pattern of chondromyxoid substance and immunocytochemistry.
The original radiologic differential diagnosis included an ependymoma, myxopapillary ependymoma
, infiltrating glioma, or, less likely, a primary nerve sheath tumor.