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Relating to myxedema.
Farlex Partner Medical Dictionary © Farlex 2012


Relating to myxedema.
Synonym(s): myxoedematous.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012


(mik-sĕ-dē′mă ) [ myx- + edema]
1. Infiltration of the skin by mucopolysaccharides, which give it a waxy or coarsened appearance and create nonpitting edema. Myxedematous skin is seen particularly in patients with hypothyroidism.
2. The clinical and metabolic manifestations of hypothyroidism in adults, adolescents, and children. myxedematous (-dem′ăt-ūs, -dēm′), adjective


The hypothyroid patient often complains of sluggishness, intolerance of cold, apathy, fatigue, and constipation. Findings may include infiltration of the subcutaneous layers of the skin by mucopolysaccharides. The hair may become dry and brittle. If the syndrome is left untreated, hypothermia, coma, and death may result.


Thyroid hormone replacement reverses the symptoms and reestablishes normal metabolic function.

childhood myxedema

Myxedema occurring before puberty.

operative myxedema

Myxedema following removal of the thyroid gland.

pituitary myxedema

Myxedema occurring secondary to anterior pituitary hypofunction.

pretibial myxedema

Edema of the anterior surface of the legs following hyperthyroidism and exophthalmos.
Medical Dictionary, © 2009 Farlex and Partners
References in periodicals archive ?
H&E staining demonstrates myxedematous stroma with prominent vessels and a striking inflammatory infiltrate composed of abundant eosinophils.
* If myxedematous coma develops, dentist should avoid any planned dental surgery.
After discovering that thyroid follicles of postmortem tissues did not contain colloid but instead they had a fibrous material, Ord associated the myxedematous state with the thyroid gland.
Cretinism can be divided into neurologic and myxedematous subtypes.
He was referred at 1 month of age with severe hypothyroidism (persistent jaundice, myxedematous face, large posterior fontanel, and umbilical hernia) and goiter.