myosin light-chain kinase


Also found in: Wikipedia.

my·o·sin light-chain ki·nase

[MIM*600922]
a calcium/calmodulin-dependent enzyme that phosphorylates the light chains of smooth muscle myosin and initiates contraction; in skeletal muscle, phosphorylation modulates tension during contraction.
References in periodicals archive ?
Said, "Mechanism of TNF-[alpha] modulation of Caco-2 intestinal epithelial tight junction barrier: role of myosin light-chain kinase protein expression," American Journal of Physiology Gastrointestinal and Liver Physiology, vol.
Black, "Smooth-muscle myosin light-chain kinase content is increased in human sensitized airways," American Journal of Respiratory and Critical Care Medicine, vol.
Tonic protein kinase A activity maintains inactive beta2 integrins in unstimulated neutrophils by reducing myosin light-chain phosphorylation: role of myosin light-chain kinase and Rho kinase.