myoglobin


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myoglobin

 [mi´o-glo″bin]
the oxygen-transporting pigment of muscle, a type of hemoprotein resembling a single subunit of hemoglobin, being composed of one globin polypeptide chain and one heme group.

my·o·glo·bin (Mb, MbCO, MbO2),

(mī'ō-glō'bin), [MIM*160000]
The oxygen-carrying and storage protein of muscle, resembling hemoglobin but containing only one subunit and one heme as part of the molecule (rather than the four of hemoglobin), and with a molecular weight approximately one quarter that of hemoglobin.
[myo- + hemoglobin]

myoglobin

(mī′ə-glō′bĭn)
n.
A single-chain, iron-containing protein found in muscle fibers, structurally similar to a single subunit of hemoglobin and having a higher affinity for oxygen than hemoglobin of the blood.

my·o·glo·bin

(mī'ō-glō'bin)
The oxygen-transporting and storage protein of muscle, resembling blood hemoglobin in function but with a molecular weight approximately one quarter that of hemoglobin. Serum levels of this protein are often measured to facilitate diagnosis of an acute myocardial infarction; it is released into the circulation within 2-4 hours after myocardial infarction, peaks at about 8-12 hours, and returns to normal after 18-24 hours.
See also: oxymyoglobin
Synonym(s): muscle hemoglobin.

myoglobin

The muscle cell equivalent of the haemoglobin of the blood. Myoglobin acts as a temporary oxygen store from which oxygen is drawn as the muscle requires it.

myoglobin

a relatively small globular protein (MW = 17 000) consisting of 153 amino acids in a POLYPEPTIDE CHAIN and one HAEM group. The molecule is found in the muscles of vertebrates and some invertebrates (giving the muscles a red colour) and has a high affinity for oxygen.

Myoglobin

A protein that holds oxygen in heart and skeletal muscle. It rises after damage to either of these muscle types.
Mentioned in: Myoglobin Test
References in periodicals archive ?
Myoglobin and lipid oxidation interactions: mechanistic bases and control.
In our study, we also examined the long-term effect of endurance training and competition on skeletal muscle damage using serum myoglobin as biomarker.
Circular dichroism (CD) spectroscopic studies of the extracted and commercial myoglobin were carried out by using Applied Photophysics Chirascan CD Spectropolarimeter.
Chakravarthy Joel et al., "Predictive value of serum myoglobin and creatine phosphokinase for development of acute kidney injury in traumatic rhabdomyolysis," Indian Journal of Critical Care Medicine, vol.
ELISA results showed lower IL-1[sz], IL-6, and TNF-a levels in the myoglobin + CLI-095 and myoglobin + PDTC groups when compared to the myoglobin-treated group [ P < 0.01; [Figure 6].{Figure 6}
Instead, the SOD2 A16V polymorphism represents a risk factor for increased muscle injury in water polo players, since athletes bearing the homozygous mutated VV16 genotype exhibited higher values of LDH, CK, CK-MB, troponin, and myoglobin than wild-type AA and heterozygous AV subjects, even if these differences were not always significant likely due to the small size of genotype subgroups.
RBC lysate (2.5 x 108 cells/ml equivalent), 2 mg/ml metHb, or 2 mg/ml myoglobin was coated onto an Immunlon-2, 96-well plate in a carbonate coating buffer (0.16 M [Na.sub.2]C[O.sub.3], 0.34 NaHC[O.sub.3], pH 9.6) overnight at 4[degrees]C.
Urine myoglobin was present in 32% of patients in Group NS and 8% of patients in Group V only.
Myoglobin increased significantly between T0 and T1 (p < 0.0001), before decreasing between T1 and T3 with the T3 levels remaining higher than T0 (p = 0.01).
These proteins were categorised into 7 types, namely; tropomyosin-1 alpha chain (TPM1), actin - alpha cardiac muscle 1 (ACTC), myosin light chain 3 - skeletal muscle isoform (MLC3F), myosin regulatory light chain2 - skeletal muscle isoform (MLC2F), myoglobin, troponin T - fast skeletal muscle (TnTf), and creatine kinase M chain (M-CK).
She told BBC News that beaked whales had very high levels of the myoglobin protein in their muscles, to the point where the tissues appeared almost black.